Discover what makes PEARLITOL® SD mannitol the industry’s first-choice excipient for direct compression, and how it can help you unlock advanced tablet dosage forms.
Direct compression excipients: Tablet formulation made simple
Direct compression is the most effective and least complex tablet manufacturing method available to producers today – but to make it a success, brands need the right excipient solutions.
Harder, better, faster, stronger: The benefits of direct compression
In contrast to other common production methods like wet granulation, direct compression requires relatively few processing steps to turn raw ingredients into high quality finished products. This simplicity offers real advantages, including reduced capital investment (in equipment and ingredients), lower labour and energy costs, improved production speed and the ability to work with water-sensitive APIs.
With proper management and the right ingredients, the direct compression method produces safe and effective tablets with no friability, sufficient hardness and a consistent disintegration and dissolution time for optimal effectiveness;
Unlock direct compression with PEARLITOL® SD mannitol
PEARLITOL® SD is an easy-to-use, spray-dried mannitol specifically designed to enhance direct compression performance.
Like all mannitol excipients, this solution offers excellent compactability and stability properties, a higher intrinsic dissolution rate compared to other binder-fillers, a semi-sweet, cool taste and enhanced flexibility thanks to its chemical inertness.
The PEARLITOL® SD mannitol difference is that it unlocks the creation of robust, high-quality tablets via direct compression without the need for additives. It also operates on a much wider range of compression forces allowing formulators to adjust manufacturing parameters to compensate for formulation performance fluctuation.
Available in two grades: PEARLITOL® 100 SD and PEARLITOL® 200 SD, this versatile solution allows formulators to choose the best particle size for their formulation; ensuring uniformity, stability and optimal organoleptic properties for more patient-friendly formulation.
Ready to get started? Learn more about PEARLITOL® SD mannitol.
Discover more about our excipients and active ingredients
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Explore our full range of excipients, raw materials and actives for pharmaceuticals, nutraceuticals, over-the-counter products, biopharmaceuticals, injectables and dialysis solutions. -
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Other solutions
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Coating
All-round benefits for patients, consumers and brands. Learn more about our coatings for hard capsules, films and taste-masking, designed for ultimate protection and performance. -
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Disintegration excipients
Explore our wide range of disintegration excipients, designed to aid the release of active ingredients in tablets or capsules. -
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Pharmaceutical fillers, diluents and binders
Discover our range of fillers, diluents and binders specially formulated to support your solid dosage forms. -
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Pharmaceutical solubilization and stability enhancers
Unlock a whole new level of quality with our range of solubilization and stability enhancers, ideal for virtually any dosage form, from solid tablets to liquid suspensions. -
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Taste-masking solutions
Get to know KLEPTOSE®, our leading range of taste-masking agents, strategically adapted to address any process or formulation constraint. -
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Excipients for liquid solutions
From syrups and solutions to ampoules and dispersions: Discover our extensive range of plant-based excipients for liquid dosage forms.
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