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PEARLITOL®

Mannitol

Roquette‘s Mannitol range is dedicated to nutraceutical and pharmaceutical oral dosage applications needing the benefit of a filler & filler/binder as well as a bulk sweetener.  The PEARLITOL® range offers a unique blend of exceptional physical and chemical stability and no hygroscopicity. Using different texturizing technologies we have designed a crystalline range of directly compressible PEARLITOL® (SD, DC and C) with various particle size allowing you to find the right product. With great organoleptic, non-cariogenic and sugar-free properties PEARLITOL® is suitable to be used in formulation addressing all type of patient population including pediatric and diabetic.

PEARLITOL® can be used in swallowable tablets; orally dispersible tablets; chewable tablets; effervescent tablets; losenges, blends, Granules, pellets premix; and medicated confectionary.
® Registered trademark(s) of Roquette Freres
    Direct Compression
    keyattribute
    High stability with no hygroscopicity
    keyattribute
    Natural Sweetness
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    Applications

    • Oral Dosage for Pharmaceutical and/or Nutraceuticals
      • Swallowable tablet
      • Orally Dispersible tablet
      • Chewable tablets
      • Effervescent tablets
      • Losenge
      • Orally Dissolving Films
      • Blends, Granules, Pellets Premix
      • Medicated Confectionary

    Functional Properties

    • Excipient
      • Filler or Filler/Binder
    • Nutrients
      • Bulk Sweetener

    Other Properties and Benefits

    • Excipact certified
    • Multicompendial
    • DMF & CEP Available

    Documents & Samples

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    Product Types

    PEARLITOL® 100 SD - #450310

    Key attributes: Particle Size Mean Diameter: 100 µm, low density
    Texturized for direct compression

    PEARLITOL® 160 C - #450001

    Key attributes: Particle Size Mean Diameter: 160 µm
    Crystal

    PEARLITOL® 200 SD - #450320

    Key attributes: Particle Size Mean Diameter: 200 µm, low density
    Texturized for direct compression

    PEARLITOL® 25 C - #450012

    Key attributes: Particle Size Mean Diameter: 25 µm
    Crystal, grinded

    PEARLITOL® 300 DC - #450108

    Key attributes: Particle Size Mean Diameter: 300 µm, high density
    Texturized for direct compression

    PEARLITOL® 400 DC - #450102

    Key attributes: Particle Size Mean Diameter: 400 µm, high density
    Texturized for direct compression

    PEARLITOL® 50 C - #450004

    Key attributes: Particle Size Mean Diameter: 50 µm
    Crystal, grinded

    PEARLITOL® 500 DC - #450103

    Key attributes: Particle Size Mean Diameter: 500 µm, high density
    Texturized for direct compression

    PEARLITOL® SW-F 200 - #450321

    Key attributes: Wheat-free
    Wheat-free mannitol powder

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    Regulation & Compliance

    Registrations may vary depending on local regulations

    Compliance

    • European Pharmacopoeia
    • United States Pharmacopeia
    • Japanese Pharmacopoeia
    • Indian Pharmacopoeia
    • (Varies by grade)

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    Help & Support

    If you need help, please get in touch with our technical team.
    Appointment
    If you feel your project needs a more in-depth discussion, please request an appointment

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    ® Registered trademark(s) of Roquette Frères or Itacel Farmoquimica Ltda. The information contained in this document is to the best of our knowledge true and accurate but all instructions, recommendations or suggestions are made without any guarantee. Since the conditions of use are beyond our control, we disclaim any liability for loss and/or damage suffered from use of these data or suggestions. Furthermore, no liability is accepted if use of any product in accordance with these data or suggestions infringes any patent. No part of this document may be reproduced by any process without our prior written permission.
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