Stabilizing microbial and biomolecule formulations
Microbes are the unsung heroes of agriculture, human health, and industrial biotechnology. In just 5ml of soil, there are more microbes than people on earth—these communities are central to plant health, crop yields, and advancements in pharmaceuticals and nutraceuticals. From biofertilizers introduced in the 19th century to today’s next-generation probiotics, biocontrol agents, and industrial enzymes, microbial and biomolecule products are booming in application and market size.
For producers—whether you’re an R&D project leader, a plant manager scaling production, or a buyer seeking the highest quality, there’s a common, critical step linking all applications: microbial stabilization. Microbial viability, shelf life, and biological functionality fundamentally depend on how you stabilize your culture post-fermentation.
Optimal stabilization for maximum viability and functionality
After large-scale fermentation, separating microorganisms (or sensitive biomolecules/enzymes) from the culture medium is only half the battle. Stabilizing these products—yeasts, bacteria, fungi, algae, enzymes, or bioactive peptides—poses substantial hurdles:
- Microbial viability and shelf life: Without optimal stabilization, cell viability plummets during storage, shipping, or field application.
- Process sensitivity: Cells and proteins are highly vulnerable to thermal stress, oxidative damage, and dehydration during techniques like spray-drying, lyophilization (freeze-drying), cryopreservation, or encapsulation.
- Functional decline: Even if products “survive” processing, loss of activity or fermentation capacity can undermine efficacy in biocontrol, probiotic, or industrial enzyme applications.
- Formulation complexity: Each strain and application demands a tailored approach—there’s no “one size fits all.”
- Sustainability requirements: End-users now demand bio-based, OMRI-listed ingredients, reducing reliance on synthetic chemicals.
Traditional stabilizers or carriers often fall short, leading to poor re-dissolution, decreased viability, or formulation instability. Microbial and enzyme stabilization is often the bottleneck between innovative R&D and commercial success.
Advanced plant-based carriers for microbial stabilization
At Roquette, we offer a scientifically proven, comprehensive portfolio specifically designed for the stabilization and formulation of microbial and biomolecule products. Our solutions are trusted across pharma, biotech, agri-input, and industrial fermentation sectors.
- GLUCIDEX® Maltodextrins: Highest purity, a wide range of dextrose equivalent (DE) values, and unrivaled batch-to-batch consistency. Maltodextrin carriers dissolve easily, are highly stable and non-reactive, and are suitable for spray-drying, lyophilization, and encapsulation. The IT grades provide optimal dispersion and reconstitution.
- Polyols portfolio (NEOSORB® Sorbitol, PEARLITOL® Mannitol, SweetPearl® Maltitol): Exceptional as cryoprotectants and bulking agents, these compounds stabilize cells and enzymes against dehydration and oxidative stress during processing (including freeze-drying and spray-drying), ensuring microbial viability and enzyme functionality upon reactivation.
- MICROCEL® microcrystalline cellulose: Functions as a water-absorbing filler, disintegrant, and flow aid for granules and tablets—assuring rapid rehydration and easy handling.
All Roquette ingredients are derived from renewable crops like corn, peas, potatoes, and wheat—fully traceable. Our proprietary processes ensure environmental responsibility (solvent-free, low-impact), reproducibility, and ingredient purity.
From Lab to Market: Co-creating your next microbial formulation
Microbial stabilization doesn’t have to be a challenge. Our biobased ingredient portfolio empower you to:
- Maximize microbial and enzyme viability during stabilization and storage
- Boost shelf life and field efficacy of your biocontrol, probiotic, or fermentation products
- Formulate with sustainable, bio-based, and OMRI-listed ingredients
- Customize your carrier, protectant, or encapsulant solution across a range of processing technologies
Discover the science and power of GLUCIDEX®, Polyols, and MICROCEL® for your next-generation fermentation products.
Contact our CTS (Customer Technical Support) team today for technical guidance, formulation trials, and commercial samples designed for your unique application and scale-up needs.
For technical specifications, application guidance, or to discuss your specific requirements, contact our technical experts to discuss your needs