A consistent disintegration and dissolution profile is critical for the delivery of your medications’ active ingredients. Discover our solutions.
Disintegration excipients: Formulation potential – released
Disintegrants and superdisintegrants are used in pharmaceutical, nutraceutical and OTC dosage forms to ensure a rapid break down into their primary particles. This allows for the effective dissolution or release of the active ingredients for enhanced patient and consumer experience.
Our disintegrant and superdisintegrant solutions
Sodium starch glycolate superdisintegrants
Suitable for all oral dosage forms and manufacturing processes – from direct compression to wet granulation – the main advantage of sodium starch glycolate is its versatility. This ingredient can also help enhance efficiency through different modes of incorporation and its ability to be used in conjunction with lubricants, with no effect on dissolution performance.
At Roquette, we offer two leading ranges of sodium starch glycolate, both featuring an array of grades designed to meet specific formulation requirements:
Derived from potato or maize starch, this range includes grades suitable for wet granulation and high-shear granulation processes, as well as pH sensitive active ingredients.
Derived from potato or corn starch, our EXPLOSOL® line is designed for use with low residual solvents.
Croscarmellose sodium superdisintegrants
With its high capacity for water absorption and complete distinegration, croscarmellose sodium is a highly effective superdisintegrant that can also serve as a dissolution aid. It is widely used in solid oral dosage forms thanks to its effectivness at low volumes and ability to regenerate after being moistened.
Roquette offers a complete portfolio of croscarmellose varieties under our SOLUTAB® range: a versatile collection of solutions ideal for use in tablets, capsules, and pellets – produced via direct compression or dry and wet granulation.
Disintegrants and self-disintegrating compounds
Our traditional native starch portfolio offers a solution for all your disintegration requirements.
- LYCATAB® C is our partially pregelatinized starch ensures a rapid disintegration and drug release.
- StarLac® is a multifunctional lactose and maize starch compound with optimized self-disintegration properties.
- PEARLITOL® FLASH is an innovative co-processed mannitol-starch compound, specially designed for fast disintegration in orodispersible applications.
Discover more about our excipients and active ingredients
Resources
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A superdisintegrant that has excellent performance and cost-benefits. -
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A highly efficient superdisintegrant with high efficiency even when used in lower doses.
Discover our solutions
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Coating
All-round benefits for patients, consumers and brands. Learn more about our film coating technology for hard capsules and tablets, designed for ultimate protection and performance.
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Direct compression
Tablet formulation made simple. Discover our solutions for direct compression without compromise.
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Fillers, Diluents and Binders
Discover our range of fillers, diluents and binders specially formulated to support your solid dosage forms.
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Solubility and stability improvement
Unlock a whole new level of quality with our range of solubilization and stability enhancers, ideal for virtually any dosage form, from solid tablets to liquid suspensions.
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Taste-masking
Get to know KLEPTOSE®, our leading range of taste-masking agents, strategically adapted to address any process or formulation constraint.
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Liquid solutions
From syrups and solutions to ampoules and dispersions: Discover our extensive range of plant-based excipients for liquid dosage forms.
Ready to start your journey?
Your formulations. Our solutions. Your success.
Get in touch with our experts to discuss your formulation goals and understand how we can make them a reality.