Liquid Forms
Roquette provides a comprehensive portfolio of plant-based excipients that address the unique challenges of liquid formulations. Our solutions enhance taste, stability, and manufacturability, ensuring reliable performance across syrups, suspensions, and solutions.
Excipients for Liquid Solutions: Liquid Polyol, Maltitol, and Sorbitol
Liquid dosage forms are essential in pharmaceutical and nutraceutical development, particularly for pediatric and geriatric patients, as well as those with swallowing difficulties. These formulations offer flexibility, patient compliance, and reliable dosing for both over-the-counter and prescription medicines. But liquid dosage forms face unique technical hurdles—crystallization, sedimentation, and active pharmaceutical ingredient (API) degradation—that require specialized excipients.
By combining broad functionality—sweetening, bulking, stabilizing, suspending, and buffering—with regulatory consistency and technical expertise, Roquette helps you achieve cost-efficient and high-quality formulations with regulatory consistency.
Our Solutions
Developing stable and palatable liquid formulations requires overcoming multiple technical challenges, from managing solubility and crystallization to controlling viscosity and taste. Roquette provides a broad portfolio of excipients designed to address these needs, ensuring reliable performance across syrups, solutions, and suspensions.
Polyols
NEOSORB® 70/70 B sorbitol and LYCASIN® 80/55 maltitol serve as sugar-free bulk sweeteners that replace sucrose while delivering a pleasant taste profile and improved dietetic properties. Their ability to reduce crystallization enhances the manufacturability of syrups, while supporting patient compliance through favorable sweetness and mouthfeel.
Glucose Syrups
GLUCIDEX® liquid glucose provides both bulking and sweetness while also contributing isotonicity, making them particularly valuable in oral and parenteral liquids. They contribute to API solubility and prevent precipitation in some syrup systems. Their versatility supports formulation robustness, offering reliable consistency and ease of processing across a wide range of applications.
Buffering Agents
Sodium gluconate helps maintain stable pH levels in sensitive formulations, protecting APIs against degradation and extending shelf life. This buffering capacity not only safeguards drug performance but also improves patient safety by maintaining product integrity over time. Its compactibility across pediatric and geriatric formulations makes it a safe and flexible option.
Suspension Agents
TABULOSE® SC co-processed microcrystalline cellulose (MCC) and carboxymethylcellulose (CMC) offers fast hydration and excellent viscosity control while preventing sedimentation in suspensions. By ensuring uniform distribution of active ingredients, it enables accurate dosing and enhances the patient experience.
Cyclodextrins
KLEPTOSE® cyclodextrins improve the solubility of poorly soluble APIs while stabilizing molecules prone to degradation or precipitation. In liquid forms, they support both efficacy and reliability, making them an indispensable tool for challenging formulations. Our hydroxypropyl-beta-cyclodextrins (HPβCDs) are pharmacopeial and accepted for oral and parenteral forms.
Our Services and Expertise
Roquette supports syrup and suspension development with our Our Customer Technical Services (CTS) laboratory expertise, providing tailored technical guidance for solubility, stability, and palatability challenges. Our team brings specialized knowledge in pediatric and geriatric formulation design including support in taste-masking strategies, osmolarity adjustment, and suspension stability, helping you create safe, compliant, and patient-friendly medicines.
Global regulatory coverage, including EP, USP, and JP monographs, ensures compliance across key markets. Sustainability is also central to our offering, with all liquid excipients derived from renewable, plant-based raw materials.
Featured liquid excipients for reliable syrup and solution design
From sorbitol to maltitol and glucose syrups, Roquette’s liquid excipient range ensures reliable performance in oral and parenteral applications.
GLUCIDEX® glucose syrups
GLUCIDEX® glucose syrups offer sweetness, bulking, and isotonicity properties, making them suitable for both oral syrups and parenteral solutions.
LYCASIN® 80/55 and 75/75 maltitol syrups
LYCASIN® 80/55 and 75/75 maltitol syrups provide sugar-free, non-cariogenic bulk sweetening. They ensure excellent taste and stable formulations with reduced crystallization risk during storage.
NEOSORB® 70/70 B sorbitol
NEOSORB® 70/70 B sorbitol solution delivers consistent sweetness, stability, and bulking functionality with non-cariogenic properties for pharmaceutical syrups and suspensions.
Our Applications
Biologics
Stabilizers, cryoprotectants, and process aids for safe, efficient biologic formulation and manufacturing.
Injectables, Dialysis and APIs
High-purity excipients ensuring biocompatibility and isotonicity in parenteral and dialysis applications.
Oral Dosage Solutions
Functional excipients improving flow, compressibility, solubility, and taste for tablets and capsules.