Dry-Powder Inhalation Solutions
Roquette’s inhalation portfolio offers an optimized excipient and high-performance capsules, ensuring consistency, stability, and efficiency for dry powder inhalers (DPIs). Our integrated approach simplifies formulation challenges, enhances drug delivery performance, and accelerates time-to-market for both innovative and generic inhaled therapies.
Optimized Inhalation Solutions for Precision and Performance: Welcome to Roquette's Inhalation Offerings
Revolutionizing Inhalation Drug Delivery
By providing a synergistic excipient and capsule solution, we address key formulation challenges such as powder flow, device compatibility, and API (active pharmaceutical ingredient) stability, helping R&D teams streamline DPI and inhalation therapy development. Unlike other suppliers, Roquette leverages its expertise in both excipients and inhalation-grade capsules to offer a seamless, high-quality formulation approach, backed by a legacy of innovation and stringent compliance with inhalation therapy requirements.
Why Choose Roquette's Inhalation Solutions?
- Precision and Performance: Our inhalation portfolio, including PEARLITOL® 200 INH mannitol and specialized inhalation-grade capsules, ensures precise dose delivery, stability, and efficiency.
- Synergy for Seamless Formulation: Combining excipient and capsule technology simplifies DPI development, offering a holistic solution for inhalation drug formulations.
- Regulatory Confidence: Backed by stringent quality standards, our solutions ensure compliance with inhalation-grade regulations.
PEARLITOL® 200 INH Mannitol
- Consistent Powder Flow: Optimized particle size distribution for even API dispersion and enhanced DPI formulation performance.
- Stability in Varying Humidity: Non-hygroscopic properties prevent caking and powder aggregation, ensuring stable formulations.
- Enhanced API Bioavailability: Optimal dose delivery and lung deposition.
- Compatibility with a wide range of APIs: Reduced chemical interactions with APIs due to very low reducing sugar.
Inhalation-grade Capsules
- Optimized Puncturing: Designed for efficient puncturing in DPI devices, ensuring consistent dose release.
- Enhanced Aerosolization: Controlled internal lubrication reduces powder adhesion, improving drug delivery efficiency.
- Flexibility in Formulation: Available in HPMC, gelatin, and low moisture options, suitable for hygroscopic and moisture-sensitive formulations.
Overcoming Inhalation Drug Delivery Challenges
Our inhalation portfolio addresses the following critical challenges faced by formulators and scientists:
- Consistent Powder Flow: PEARLITOL® 200 INH mannitol ensures even API dispersion, enhancing DPI performance.
- API Stability: Our excipient and capsules maintain stability avoiding moisture and chemical interactions, thus ensuring long-term efficacy.
- Reliable DPI Performance: Specialized capsules guarantee consistent puncturing and powder release.
- Regulatory and Safety Compliance: Our products comply with pharmacopeias, ICH Q3D, and nitrosamine regulations, ensuring safety and quality.