Solid forms - Tablets
Roquette is a global leader in plant-based excipients for solid oral dosage forms, offering a portfolio that includes fillers, binders, disintegrants, solubilizers, taste-masking agents, and multifunctional solutions. Combined with decades of formulation expertise and dedicated Customer Technical Services (CTS), we help formulators meet evolving patient expectations and regulatory demands with confidence.
High-Quality Excipients for Solid Tablet Manufacturing
Tablets remain the most widely used oral dosage form, valued for their convenience, accuracy, and cost-efficiency. From simple swallowable tablets to more advanced orally dispersible, chewable, and effervescent forms, each design requires excipients that provide functionality, patient compliance, and manufacturing consistency.
Our Solutions
Developing reliable, patient-friendly solid oral tablets requires excipients that perform consistently across a range of manufacturing processes. Roquette offers comprehensive formulation solutions tailored to simplify production while achieving the desired tablet performance, whether for direct compression, orodispersible, chewable, effervescent, or controlled-release formats.
Each solution integrates functionality, stability, and manufacturability, supporting the needs of pharmaceutical and nutraceutical developers worldwide.
Direct Compression
Direct compression remains one of the most efficient tablet manufacturing methods, requiring excipients with excellent flow, compressibility, and uniformity. Roquette’s range of mannitol, starches, and co-processed excipients are specifically engineered to deliver robust mechanical strength and content uniformity, even in high-speed production environments. These ingredients help formulators reduce process steps, optimize powder handling, and maintain consistent tablet weight and hardness, making them ideal for both standard and sensitive formulations.
Orodispersible Tablets (ODTs)
Orodispersible tablets are designed for rapid disintegration in the mouth without the need for water, enhancing convenience and compliance across patient populations. Excipients such as PEARLITOL® Flash co-processed mannitol-starch provide the balance of fast disintegration, pleasant mouthfeel, and structural robustness needed for ODT formats. These excipients help achieve uniform dispersion and high compressibility, allowing manufacturers to produce ODTs with both sensory appeal and reliable mechanical performance.
Chewable and Effervescent Tablets
Palatability and stability are key to successful chewable and effervescent tablet design. Roquette’s polyols, including SweetPearl® maltitol, NEOSORB® sorbitol, and XYLISORB® xylitol, deliver superior taste, smooth texture, and low hygroscopicity, ensuring tablets remain stable and pleasant to consume. These excipients support flexible formulation strategies for chewable dosage forms, medicated confectionery, and effervescent applications where sensory experience is central to patient acceptance and compliance.
Controlled Release
Controlled release tablets require excipients that maintain a predictable drug release profile and robust tablet integrity. Roquette’s PEARLITOL® CR-H co-processed mannitol-HPMC simplifies controlled release formulation by combining excellent compressibility with sustained-release functionality. This multifunctional system enables formulators to streamline development while achieving consistent performance, mechanical strength, and therapeutic delivery across batch runs.
Disintegration and Dissolution
Achieving consistent disintegration and dissolution is critical to ensuring dosage reliability and bioavailability. Roquette provides a range of proven disintegrants and multifunctional excipients to meet this need, including GLYCOLYS® sodium starch glycolate, SOLUTAB® croscarmellose sodium, and StarLac® co-processed lactose-starch. These materials promote rapid tablet breakup and uniform dissolution, improving product performance across immediate- and fast-release formats while supporting regulatory and patient requirements for consistency.
Our Services and Expertise
Roquette’s Customer Technical Services (CTS) team provides hands-on formulation support that helps pharmaceutical and nutraceutical developers optimize solid oral dosage performance. CTS has supported partners improve tablet hardness and disintegration balance when developing direct compression and orodispersible formulations. By fine-tuning excipient ratios, such as combining mannitol grades within the PEARLITOL® range, our specialists have helped achieve improved compressibility and dissolution without compromising taste or stability.
With global innovation hubs and decades of formulation experience, Roquette’s CTS ensures reliable, reproducible outcomes across manufacturing environments. This technical partnership reflects our ongoing commitment to innovation, performance, and collaboration in solid oral dosage development.
Our Featured Products
GLYCOLYS® sodium starch glycolate
GLYCOLYS® sodium starch glycolate is a reliable superdisintegrant for pharmaceutical and nutraceutical tablets and capsules. GLYCOLYS® ensures rapid and consistent disintegration, supporting both standard and orally dispersible tablet formats.
PEARLITOL® mannitol
PEARLITOL® mannitol is a versatile filler and filler/binder with exceptional physical and chemical stability. The crystalline PEARLITOL® range provides multiple particle sizes to optimize flow and compressibility. Non-hygroscopic and sugar-free, it is suitable for a wide range of patient populations, including pediatric and diabetic applications.
SweetPearl® maltitol
SweetPearl® maltitol powder is a stable, low-hygroscopicity filler/binder that supports formulation flexibility. Available in multiple particle sizes and densities, SweetPearl® can be used in swallowable, chewable, and effervescent tablets, as well as coatings and medicated confectionery.
Our Applications
Biologics
Stabilizers, cryoprotectants, and process aids for safe, efficient biologic formulation and manufacturing.
Injectables, Dialysis and APIs
High-purity excipients ensuring biocompatibility and isotonicity in parenteral and dialysis applications.
Oral Dosage Solutions
Functional excipients improving flow, compressibility, solubility, and taste for tablets and capsules.