Amylose is a rather linear molecule. In aqueous solution it forms easily helical structures having a hydrophobic cavity. This non polar cavity permits the formation of inclusion compounds with various guest molecules, analogue with Cyclodextrins. The interaction of amylose with numerous other molecules is widely described in the literature.
Whereas cyclodextrins and its derivatives are extensively used to make inclusion compounds, all attempts to use amylose rich starches for similar applications have failed. This may be caused by analytical, problems but also by the poor solubility of pure amylose having a high molecular weight. A new cold water soluble material with higher amount of amylose is available. Its potential to solubilise drugs has been investigated.