Whereas cyclodextrins and its derivatives are extensively used to make inclusion compounds, all attempts to use amylose rich starches for similar applications have failed. This may be caused by analytical, problems but also by the poor solubility of pure amylose having a high molecular weight. A new cold water soluble material with higher amount of amylose is available. Its potential to solubilise drugs has been investigated.
Case study: KLEPTOSE® BIOPHARMA as a potential functional alternative to surfactants within biologic formulationsKLEPTOSE® BioPharma (hydroxypropyl beta cyclodextrin) represents a promising alternative to surfactants commonly used within biologic formulations, such as polysorbates.
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