Please note our Product Finder does not contain our complete product portfolio. Should you wish for further information on a specific product, please contact us.
Contact customer care
Your product sample is added to basket

Mannitol Pyrogen Free Grade

"PEARLITOL® PF Mannitol pyrogen-free grade is used for parenteral preparations and Rx injectables.   As an API it serves as an osmotic diuretic agent in small and large volume parenteral injectables.  As an excipient it is used for Rx injectables as an isotonic agent and a bulking agent for freeze dried powder for injection or infusion. 

Mannitol pyrogen-free is also used to reduce elevated pressure in the brain (cerebral oedema) and in the eyes. In these critical solutions, mannitol acts as a pharmaceutical active ingredient and its production has to comply with the internationally accepted GMP standards. 

Due to its physical and chemical properties mannitol is the choice excipient for freeze-dried powder for injection or infusion. "

® Registered trademark(s) of Roquette Frères
    Pyrogen Free
    DMF/CEP Available
    GMP Certificate


    • Injectables
      • Large Volume Parenteral
      • Rx Injectables

    Functional Properties

    • Excipient
      • Bulking Agent
      • Isotonic Agent
    • API
      • Osmotic Diuretic Agent

    Other Properties and Benefits

    • White crystalline powder

    Documents & Samples

    Select an area
    To better serve you and give you exactly the information you need, select an area so we can verify that the product is available for sale there.
    When a product is verified 'available for sale' in an area, you can be assured that Roquette has met all the standards and registrations required by that area's regulatory authorities.
    Usage country:
    Usage Area Selected
    Please select the usage area to continue
    Product not available for sale
    Unfortunately Mannitol Pyrogen Free Grade are not available in $country.

    Product Types

    PEARLITOL® PF - #450002

    Key attributes: High purity, consistency, and pyrogen-free
    Unfortunately this product is not available for sampling

    Pyrogen-free mannitol for intracranial application 


    {{}} {{}}

    Key attributes:
    • {{attribute}}
    You may order up to 3 samples per product.
    This comment must be less than 250 chars
    Form errors
    • {{error}}
    Server Error.
    We are unable to carry out a sample order right now.
    Please try again later or alternatively you can contact us.
    Server Error.
    Order now

    Regulation & Compliance

    Registrations may vary depending on local regulations


    • European Pharmacopoeia
    • United States Pharmacopeia
    • Japanese Pharmacopoeia
    • Indian Pharmacopoeia
    • (Varies by grade)


    • A CEP and Drug Master File (DMF) are available. Please contact us to discuss this information.

    Need more support ?

    Help & Support

    If you need help, please get in touch with our technical team.
    If you feel your project needs a more in-depth discussion, please request an appointment
    The information available here is not intended to indicate that a specific product is available or approved for sale in a country. It is meant to provide general information about our products and facilities. Should you have any specific questions about the availability of a product in particular, please click here.
    • {{productType.nameProductType}} - {{productType.idProductType}}
      • {{ document.disclaimer }}
    Server Error.
    We are unable to carry out a download document right now.
    Please try again later or alternatively you can contact us.

    Make An Enquiry

    Entering your details below will send your query to the relevant team for a swift and helpful response. We will not use your details for anything other than replying to your query.

    Product Details

    Your Details