Biologics
Confidence is key to successful drug development. Roquette’s biopharmaceutical solutions are designed to support every stage of biologics formulation and manufacturing, from cell culture to final purification. With decades of experience in carbohydrate chemistry and a vertically integrated supply chain, Roquette provides the high-quality excipients and raw materials needed to ensure stability, solubility, and performance in complex biopharmaceutical applications.
Advancing Biopharmaceutical Formulation with Confidence
By partnering with Roquette, manufacturers gain access to consistent, reliable ingredients backed by strong regulatory expertise and global technical support. Whether developing advanced protein-based therapeutics, viral vectors, or cell and gene therapies, Roquette’s biopharma portfolio helps accelerate time-to-market while maintaining uncompromising quality and safety standards.
Our Solutions
Roquette’s biopharmaceutical solutions support innovation across the full drug development lifecycle. With a vertically integrated supply chain and extensive formulation expertise, Roquette enables manufacturers to achieve superior safety, quality, and scalability. Each excipient in our BioPharma portfolio is developed to meet the industry’s highest standards for purity, consistency, and performance, helping ensure reliable results in even the most sensitive formulations.
Sorbitol
NEOSORB® sorbitol is a non-pyrogenic stabilizer that helps maintain protein conformation and prevent aggregation. It provides reliable tonicity adjustment and supports formulation stability for biologics, vaccines, and injectable therapies. Its low endotoxin profile and batch-to-batch reproducibility make it ideal for high-purity applications.
Mannitol
PEARLITOL® mannitol provides structural integrity and protein protection during lyophilization. With low endotoxin levels and excellent crystallinity, it enhances formulation stability, reconstitution behavior, and shelf life. Widely used in vaccines, monoclonal antibodies, and recombinant protein products, mannitol helps maintain bioactivity and product consistency.
Dextrose Anhydrous
Dextrose Anhydrous BioPharma delivers reliable, consistent performance as an essential energy and carbon source for mammalian and microbial cell cultures. Its low endotoxin content and tight quality controls support robust cell growth and high protein yields. Backed by Roquette’s vertically integrated supply chain, it ensures dependable availability and reproducibility for large-scale biologics manufacturing.
Dextrose Monohydrate
LYCADEX® BioPharma low endotoxin grade dextrose monohydrate provides a highly consistent and pure energy source for upstream cell culture applications. Designed to support optimal cell growth and productivity, it helps maintain healthy metabolic activity and stable process yields in biologics manufacturing. Its low endotoxin specification and multi-compendial compliance (EP, USP, JP) make it a trusted choice for demanding biopharmaceutical processes where reliability and reproducibility are essential.
Hydroxypropyl Beta-cyclodextrins
KLEPTOSE® HP and HPB hydroxypropyl beta-cyclodextrins enhance protein solubility, prevent aggregation, and support viral inactivation in advanced biologic and gene therapy applications. Their ability to form inclusion complexes with hydrophobic molecules improves formulation clarity and performance across both liquid and lyophilized systems. Kleptose excipients are a cornerstone of Roquette’s innovation in stabilizing sensitive biomolecules.
Single-Use Packaging Solutions
Central to these solutions is single-use disposable packaging, which ensure precise delivery while reducing manual handling and the potential for contamination. But Roquette’s single-use packaging solutions are so much more than single-use chargebags. They are purpose-built to:
- Reduce Handling Times: Minimize manual interventions to enhance efficiency.
- Mitigate Risk: Lower the potential for contamination and cross-contamination.
- Enhance Efficiencies: Streamline processes to accelerate production timelines.
- Safeguard Supply: Ensure a reliable and consistent supply chain.
- Accelerate Time-to-Market: Bring products to market more swiftly without compromising quality.
Biopharma Solutions for Safe, Stable, and Scalable Drug Development
Roquette’s biopharmaceutical excipients are designed to support reliable, high-quality formulations across the drug development lifecycle. From upstream cell culture to downstream protein stabilization, each product in our portfolio delivers consistent performance, regulatory confidence, and supply chain reliability.
Your Partner in Biopharmaceutical Success
Roquette supports biopharmaceutical manufacturers with a comprehensive suite of services and innovations designed to optimize formulation development and manufacturing efficiency. Central to this support is Customer Technical Services (CTS), which provides expert guidance throughout the product lifecycle, from excipient selection and formulation optimization to process troubleshooting and regulatory compliance.
Through CTS, manufacturers gain access to:
- Formulation expertise for proteins, viral vectors, and cell & gene therapies
- Process development support to ensure reproducibility and scalability
- Regulatory guidance to navigate global requirements and documentation
In addition, Roquette continuously invests in excipient innovation, developing solutions such as KLEPTOSE® HP and HPB for protein stabilization, solubility enhancement, and viral inactivation. These innovations, combined with Roquette’s vertically integrated supply chain and quality assurance, provide manufacturers with the tools and confidence needed to deliver safe, effective, and consistent biopharmaceutical products.
Discover More About the Markets We Serve
Consumer Healthcare
Plant-based ingredients and excipients, as well as capsules, for nutraceuticals, over-the- counter (OTC) products, and functional supplements that combine efficacy with consumer appeal.
Pharmaceuticals
Explore excipients, formulation solutions, and capsules, designed to enhance stability, performance, and patient compliance in oral and parenteral dosage forms.