KLEPTOSE® HPB BIOPHARMA
KLEPTOSE®
®Registered Trademark(s) of Roquette Frères
- Very high purity
- Low endotoxin
- For application in BioPharma
Lower level of molecular substitution (MS) = 0.62
Applications
- Single-use Manufacturing
- Downstream
Functional properties
- Protein Stabilization
- Precision Dispense
Documents
Product Specification Sheet
Name
Region
Size
Download
KLEPTOSE® HPB BioPharma
476,35 Ko
Region :
476,35 Ko
Safety Data Sheet
Name
Region
Language
Size
Download
KLEPTOSE® HPB BioPharma
Oceania, AU
EN
265,52 Ko
Region : Oceania, AU
EN
265,52 Ko
KLEPTOSE® HPB BioPharma
Americas, CA
EN
276,23 Ko
Region : Americas, CA
EN
276,23 Ko
KLEPTOSE® HPB BioPharma
Europe, CH
EN
512,10 Ko
Region : Europe, CH
EN
512,10 Ko
KLEPTOSE® HPB BioPharma
Asia, CN
EN
319,13 Ko
Region : Asia, CN
EN
319,13 Ko
KLEPTOSE® HPB BioPharma
Europe, DE
EN
514,78 Ko
Region : Europe, DE
EN
514,78 Ko
KLEPTOSE® HPB BioPharma
Europe, FI
EN
511,74 Ko
Region : Europe, FI
EN
511,74 Ko
KLEPTOSE® HPB BioPharma
Europe, FR
EN
512,11 Ko
Region : Europe, FR
EN
512,11 Ko
KLEPTOSE® HPB BioPharma
Europe, GB
EN
375,46 Ko
Region : Europe, GB
EN
375,46 Ko
KLEPTOSE® HPB BioPharma
Europe, IT
EN
515,00 Ko
Region : Europe, IT
EN
515,00 Ko
KLEPTOSE® HPB BioPharma
Asia, IN
EN
263,49 Ko
Region : Asia, IN
EN
263,49 Ko
KLEPTOSE® HPB BioPharma
Americas, CA
FR
387,05 Ko
Region : Americas, CA
FR
387,05 Ko
KLEPTOSE® HPB BioPharma
Europe, CH
DE
523,89 Ko
Region : Europe, CH
DE
523,89 Ko
KLEPTOSE® HPB BioPharma
Europe, CH
FR
626,44 Ko
Region : Europe, CH
FR
626,44 Ko
KLEPTOSE® HPB BioPharma
Europe, CH
IT
612,15 Ko
Region : Europe, CH
IT
612,15 Ko
KLEPTOSE® HPB BioPharma
Asia, CN
ZH
630,44 Ko
Region : Asia, CN
ZH
630,44 Ko
KLEPTOSE® HPB BioPharma
Europe, DE
DE
528,64 Ko
Region : Europe, DE
DE
528,64 Ko
KLEPTOSE® HPB BioPharma
Europe, DK
DA
521,38 Ko
Region : Europe, DK
DA
521,38 Ko
KLEPTOSE® HPB BioPharma
Europe, ES
ES
526,74 Ko
Region : Europe, ES
ES
526,74 Ko
KLEPTOSE® HPB BioPharma
Europe, FI
FI
528,09 Ko
Region : Europe, FI
FI
528,09 Ko
KLEPTOSE® HPB BioPharma
Europe, FR
FR
624,41 Ko
Region : Europe, FR
FR
624,41 Ko
KLEPTOSE® HPB BioPharma
Americas, Asia, Oceania, Africa
PT
280,30 Ko
Region : Americas, Asia, Oceania, Africa
PT
280,30 Ko
KLEPTOSE® HPB BioPharma
Americas, Asia, Oceania, Africa
RU
405,21 Ko
Region : Americas, Asia, Oceania, Africa
RU
405,21 Ko
KLEPTOSE® HPB BioPharma
Europe, IT
IT
616,12 Ko
Region : Europe, IT
IT
616,12 Ko
KLEPTOSE® HPB BioPharma
Asia, KR
KO
318,04 Ko
Region : Asia, KR
KO
318,04 Ko
KLEPTOSE® HPB BioPharma
Asia, JP
JA
391,66 Ko
Region : Asia, JP
JA
391,66 Ko
Get in touch with our Technical Experts
Please feel free to contact our technical experts for support during the development process.
Technical data
| Synonyms | HYDROXYPROPYLBETADEX |
|---|---|
| CAS number | 128446-35-5 |
| Physical form or apperance | White or almost white amorphous powder. The statistical hydroxypropylation of beta-cyclodextrin creates a multitude of molecules, differing by the position of the hydroxypropyl groups. Consequently, the product is not able to crystallize and remains in the amorphous state. |
| Application | KLEPTOSE® HPB biopharma hydroxypropyl β-cyclodextrin. It is a low endotoxin pyrogen-free solution for protein stabilization. It exhibits surface activity and anti-aggregation properties for therapeutic proteins shelf-life extension. KLEPTOSE® HPB Biopharma also enables to reduce thermal and agitation sensitivity of formulations. |
| Water sorption isotherm at 20°C |
|
| Chemical Structure |
|
| Glass Transition Temperature vs. Water Content |
|
| Viscosity in water at 2°C |
|
| Surface Tension |
|
| Osmolality |
|
| Average molecular weight | 1387 g/mol |
| Nominal Water content (LOD) | 4.00 |
| Maximal Water content (LOD) | 10.00 |
| Nominal molar substitution | 0.62 |
| Minimum Molar substitution range | 0.58 |
| Maximum Molar substitution range | 0.68 |
| Solubility | Highly soluble in water. At high concentration, the wetting and dissolution time of the powder is delayed due to its low density and increased viscosity. Soluble in ethanol. Freely soluble in propylen glycol. |
| Glass Transition Temperature of the Cryo-Concentrated Phase | -10.30 |
| Maximum bacterial endotoxins | 5 |