KLEPTOSE®
Low endotoxin hydroxypropyl beta-cyclodextrin
Available in 1, 10 and 25kg plastic drums, and Roquette Precision Dispense packaging
KLEPTOSE® HP and HPB BioPharma Low endotoxin hydroxypropyl beta-cyclodextrin is a multifunctional excipient that provides protein stabilization in biopharmaceutical downstream applications. These are cyclic oligosaccharides with a bucket-like structure. With a hydrophobic internal cavity and hydrophilic exterior, these starch derivatives can encapsulate molecules, forming inclusion complexes where lipophilic compounds are non-covalently bound within the cavity.Their unique function to encapsulate and shield water insoluble materials can be utilized to shield exposed hydrophobic residues on aggregation-prone proteins, thereby modulating protein aggregation. Widely used in the formulation of small molecules, highly soluble beta-cyclodextrin derivatives like our KLEPTOSE® HP BioPharma and KLEPTOSE® HPB BioPharma show promise as a multifunctional excipient suitable for biopharma applications.
Representing a promising class of excipients that can reduce protein aggregation induced by physical stress, cyclodextrins can serve as an alternative option to currently used excipients, or a tool to synergistically complement your biotherapeutic formulations.
These materials are suitable for use in biopharmaceutical manufacturing and as an excipient for injectable dosage forms. Contact us today at Roquette to talk to us about these multicompendial materials - EP, USP and JP.
® Registered trademark(s) of Roquette Frères
Innovative new solution for protein stabilization
Multi-compendial
Sole custody of the supply chain
Applications
- Downstream
- Single-use Manufacturing
Functional Properties
- Protein Stabilization
- Precision Dispense
Other Properties and Benefits
- Freely soluble in water
- Freely soluble in propylene glycol
- White or almost white powder
- Amorphous or crystalline powder
Documents & Samples

Select an area
To better serve you and give you exactly the information you need, select an area so we can verify that the product is available for sale there.
?
When a product is verified 'available for sale' in an area, you can be assured that Roquette has met all the standards and registrations required by that area's regulatory authorities.
Usage country:
Usage Area Selected
Please select the usage area to continue
Product not available for sale
Unfortunately Low endotoxin hydroxypropyl beta-cyclodextrin are not available in $country.
Product Types
KLEPTOSE® HP BIOPHARMA - #346105
Key attributes:
Very high purity, Low endotoxin, For application in BioPharma
Unfortunately this product is not available for sampling
Higher level of molecular substitution (MS) = 0.90
KLEPTOSE® HPB BIOPHARMA - #346113
Key attributes:
Very high purity, Low endotoxin, For application in BioPharma
Unfortunately this product is not available for sampling
Lower level of molecular substitution (MS) = 0.62
Order
Server Error.
Order now
Regulation & Compliance
Registrations may vary depending on local regulations
Compliance
- European Pharmacopoeia
- United States Pharmacopeia
- Japanese Pharmacopoeia
Regulatory
- Manufacture: ICH-Q7 or IPEC PQG GMP - Production and packaging
- Distribution: IPEC Good Distribution Practices
- Registrations vary depending on local regulations.
Need more support ?
Help & Support
If you need help, please get in touch with our technical team.
Appointment
If you feel your project needs a more in-depth discussion, please request an appointment
The information available here is not intended to indicate that a specific product is available or approved for sale in a country. It is meant to provide general information about our products and facilities. Should you have any specific questions about the availability of a product in particular, please click here.
Server Error.
We are unable to carry out a download document right now.
Please try again later or alternatively you can contact us.
Please try again later or alternatively you can contact us.