Learn more about our commitment to supporting the development of health-boosting nutraceuticals and OTC consumer products.
Solubility and stability improvement
We offer a full range range of solubilization and stability enhancers: native and hydroxypropyl cyclodextrins KLEPTOSE®, and octenyl succinate starches CLEARGUM® CO, for use in many dosage forms, from solid to liquid.
Native betacyclodextrins
Molecular inclusion complexes using cyclodextrins have become an common formulation strategy to improve the solubility or stability of active ingredients.
Roquette has pioneered the development of betacyclodextrin technology, developing a full range of KLEPTOSE® betacyclodextrins. With different powder properties, chemical substitutions and solubility profiles, they are able to meet modern formulation needs.
Octenyl succinate starches
CLEARGUM® CO are amphiphilic polymers providing multiple functions:
- Decreases surface tension for the stability of your emulsions (liquid or solid)
- Increases wettability of your API and speed of dissolution
- Improves directly API solubility in water via its stabilization
Hydroxypropyl betacyclodextrins
Push back your formulation limits with our hydroxypropyl betacyclodextrins enabling technology: KLEPTOSE® HPB, HP and KLEPTOSE® PB-LB. For a long time, hydroxypropyl betacyclodextrins technology has been used exclusively by a select few. Today, the patent environment for HPBCD is more favourable for new formulations and the use of HPBCD technology in pharmaceuticals is now free of any broad-use restrictions except within the sole US territory till 2019.
You no longer have to let a poorly soluble active ingredients limit your formulation power!
Discover more about our excipients and active ingredients
Resources
-
![An older couple holds up a bottle of tablets.]()
-
![A woman with brown hair, wearing a white coat, checking a machine in a pharmaceutical laboratory]()
Don’t let poor bioavailability hold you back. Advance your oral dosage forms with our versatile solubilizing solutions. -
![A little girl with pigtails and a pink striped t-shirt has an orodispersible tablet on her tongue]()
When it comes to meeting the challenges of formulation, you need more than just an ingredient supplier.
Other solutions
-
![pharma tablet film coating woman]( "pharma tablet film coating woman")
Coating
Use a film coating to mask unpleasant odors and tastes, and protect drugs from environmental factors. A benefit for both patient and laboratory. -
![Pharma - Womand taking a tablet produced via direct compression]( "Pharma - Womand taking a tablet produced via direct compression")
Direct compression
Tablet formulation made simple: your guide to direct compression without compromise. -
![pharma oral dosage form tablet]( "pharma oral dosage form tablet")
Fillers, Diluents and Binders
Discover the variety of fillers, diluents and binders Roquette offers for the formulation of your solid dosage forms. -
![Taste-masking child syrup]( "Taste-masking child syrup")
Taste-masking
Discover our full range of KLEPTOSE®, efficient taste-masking agents adapted to all process and formulation constraints you might have. -
![pharma orodispersible form]( "pharma orodispersible form")
Disintegrants and Superdisintegrants
Roquette's wide range of disintegration excipients facilitate the dissolution or release of the active ingredients of your capsules or tablets. -
![pharma-oral-dosage-forms-syrup-little-boy]( "pharma-oral-dosage-forms-syrup-little-boy")
Liquid solutions
Roquette offers a large range of plant-based excipients for the formulation of liquid forms: syrups, solutions, ampoules, dispersions, etc.
Learn more about our solutions?
Your success is our greatest priority, and your needs are unique. We would love to better understand your needs and connect you with our experts.
Need more information about this solution?