PEARLITOL® PF pyrogen-free mannitol is used for parenteral preparations and provides excipient and API benefits.
As an excipient, it is an isotonic agent and a bulking agent for freeze-dried powder for injection or infusion.
As an API, it offers various functionalities: osmotic diuretic agent in small and large volume parenteral injectables, diagnostic agent for kidney function, adjunct in the treatment of an acute renal failure, reduction of intracranial pressure in the treatment of cerebral oedema, reduction of intraocular pressure and detoxifier.
Water content (LOD)
Water Content (LOD) Maximum: 0.5 %
Very soluble in water (216 mg/ml of water at 25 °C), practically insoluble in ethanol.
Minimum melting temperature : 166 °C
Maximum melting temperature: 170 °C
Water sorption isotherm at 20°C
Glass Transition Temperature of the Cryo-Concentrated Phase Tg'
These typical values are provided for information only and we believe them to be reliable. Methods available upon request.