MICROCEL® MC-200
Microcrystalline Cellulose
Product Profile

MICROCEL® MC-200
Microcrystalline Cellulose

EP/USP-NFcompliance

 

Product Name

MICROCEL® MC-200 Microcrystalline Cellulose

Synonyms

Cellulose, Microcrystalline

CAS Number

9004-34-6

Chemical Structure

Physical Form or Appearence

White, non-fibrous powder

Application

MICROCEL® MC-200 / Microcrystalline Cellulose is a direct compression excipient and fiber source for pharmaceutical oral dosage and nutraceutical forms. It is also suitable for capsule filling.

Water Content (LOD)

Maximum water content: 7 %

Morphology

Average Mean Particle Diameter

180 µm

Particle Size Distribution by Laser Diffraction

dv10 = 65.8 µm
dv50 = 198 µm
dv90 = 385 µm

Solubility

Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents.

Water sorption isotherm at 20°C

Taste/Odor

Odorless and tasteless  

Compression Behaviour

Experimental Conditions for Compression Behavior

Tablet Press  STYLCAM 200R 
Production Speed  40 tablets/min (linear punch velocity: 152 mm/s; simulated rotary press speed: 250000 tablets/hour) 
Tooling  10 mm Flat punch 
Lubrication  No lubricant 
Tablet Mass  400 mg 

Powder Characteristics

Powder Flowability (according to Ph.Eur. 2.9.16, 10mm outflow opening): 8 s

Bulk Density: 0.37 g/cm3
Tapped Density: 0.49 g/cm3
True Density: 1.54 g/cm3

Specific surface area: 0.8 m2/g
Angle of Repose: 36 °

 

Disclaimer

® Registered trademark(s) of Roquette Frères. Any information provided herein is intended for healthcare and food industry professionals for internal use only and not to be delivered as such to final consumers. Information is based on our current state of knowledge and made available on an informational basis; products described may have restrictions with respect to their use, communication, and/or usage levels, and such may vary on a country-by-country basis. Manufacturers of dietary supplements should evaluate the intended use of the particular ingredient in their finished dietary supplement to confirm compliance with the applicable laws and regulations of authorities regulating such products, because the suitability and regulatory status of a product may be dependent on its specific intended use. As the use of these products is beyond our control, Roquette makes no express or implied warranties regarding the use of the product and no guarantee of product properties, and in particular no express or implied warranties regarding the use of the product in dietary supplements, including without limitation the implied warranties of merchantability and fitness for a particular purpose, and Roquette disclaims liability for any loss and/or damage related to such use. Roquette, further, does not warrant that the information or its use will not infringe any patent or other proprietary rights of any third party. Roquette providing this information is not a commitment to sell any product encompassing any of such information in the future.

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