KLEPTOSE® HPB Parenteral grade
Hydroxypropyl β-Cyclodextrin - Pyrogen-free - Low molar substitution

KLEPTOSE® HPB Parenteral grade Pyrogen-free Hydroxypropyl β-cyclodextrin

128446-35-5

Nominal molecular weight: 1387 g/mol

White or almost white amorphous powder.
The statistical hydroxypropylation of beta-cyclodextrin creates a multitude of molecules, differing by the position of the hydroxypropyl groups.
Consequently, the product is not able to crystallize and remains in the amorphous state.

KLEPTOSE® HPB for parenteral uses. It is a pyrogen-free solution that improves drug solubility and stability against light or oxidation by molecular encapsulation. It also reduces irritation at injection site.

Nominal molar substitution: 0.62
Molar substitution range: 0.58-0.68

Highly soluble in water. At high concentration, the wetting and dissolution time of the powder is delayed due to its low density and increased viscosity.
Soluble in ethanol.
Freely soluble in propylen glycol.