KLEPTOSE® HPB Parenteral grade
Hydroxypropyl β-Cyclodextrin - Pyrogen-free - Low molar substitution
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Product Name
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KLEPTOSE® HPB Parenteral grade Pyrogen-free Hydroxypropyl β-cyclodextrin |
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Synonyms
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HYDROXYPROPYLBETADEX
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CAS Number |
128446-35-5 |
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Chemical Structure
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Molecular Weight |
Nominal molecular weight: 1387 g/mol |
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Physical Form or Appearance |
White or almost white amorphous powder. |
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Application |
KLEPTOSE® HPB for parenteral uses. It is a pyrogen-free solution that improves drug solubility and stability against light or oxidation by molecular encapsulation. It also reduces irritation at injection site. |
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Water Content (LOD)
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Nominal water content: 4%
Maximum water content: 10% |
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Degree of Substitution |
Nominal molar substitution: 0.62 |
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Solubility
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Highly soluble in water. At high concentration, the wetting and dissolution time of the powder is delayed due to its low density and increased viscosity. |
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Water sorption isotherm at 20°C
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Glass transition Temperature vs. water content
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Glass transition temperature of the cryo-concentrated phase (Tg’)
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Tg’=-10.3°C
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Viscosity in water
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Surface Tension in Water |
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Osmolality
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