KLEPTOSE® HPB-LB Parenteral grade
Hydroxypropyl β-Cyclodextrin - Pyrogen-free - Medium molar substitution
EP/USP/CHP compliance
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Product Name
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KLEPTOSE® HPB-LB Parenteral grade Pyrogen-free Hydroxypropyl β-cyclodextrin |
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Synomyms
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HYDROXYPROPYLBETADEX
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CAS Number
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128446-35-5 |
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Chemical Structure
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Molecular Weight |
1338-1424 g/mol |
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Physical Form or Appearance
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White or almost white amorphous powder. |
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Application |
KLEPTOSE® HPB-LB for parenteral use. It is a pyrogen-free solution that improves drug solubility and stability against light or oxidation by molecular encapsulation. It also reduces irritation at injection site. KLEPTOSE® HPB-LB is a multi-compendial product that complies with European and U.S. Pharmacopeia, and has standards that not only comply with but are even higher than Chinese Pharmacopeia. |
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Water Content (LOD) |
Maximum water content: 10 % |
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Degree of Substitution |
Molar substitution range: 0.50-0.71 |
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Solubility
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Highly soluble in water. At high concentration, the wetting and dissolution time of the powder is delayed due to its low density and increased viscosity. |
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Water sorption isotherm at 20°C |
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Glass Transition Temperature vs. Water Content |
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Glass transitiontemperature of the cryo-concentrated phase (Tg’) |
Tg’=-11,1°C
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Disclaimer
® Registered trademark(s) of Roquette Frères. Any information provided herein is intended for healthcare and food industry professionals for internal use only and not to be delivered as such to final consumers. Information is based on our current state of knowledge and made available on an informational basis; products described may have restrictions with respect to their use, communication, and/or usage levels, and such may vary on a country-by-country basis. Manufacturers of dietary supplements should evaluate the intended use of the particular ingredient in their finished dietary supplement to confirm compliance with the applicable laws and regulations of authorities regulating such products, because the suitability and regulatory status of a product may be dependent on its specific intended use. As the use of these products is beyond our control, Roquette makes no express or implied warranties regarding the use of the product and no guarantee of product properties, and in particular no express or implied warranties regarding the use of the product in dietary supplements, including without limitation the implied warranties of merchantability and fitness for a particular purpose, and Roquette disclaims liability for any loss and/or damage related to such use. Roquette, further, does not warrant that the information or its use will not infringe any patent or other proprietary rights of any third party. Roquette providing this information is not a commitment to sell any product encompassing any of such information in the future.