KLEPTOSE® HPB-LB Parenteral grade
Hydroxypropyl β-Cyclodextrin - Pyrogen-free - Medium molar substitution
EP/USP/CHP compliance
Product Name
|
KLEPTOSE® HPB-LB Parenteral grade Pyrogen-free Hydroxypropyl β-cyclodextrin |
Synomyms
|
HYDROXYPROPYLBETADEX
|
CAS Number
|
128446-35-5 |
Chemical Structure
|
![]() |
Molecular Weight |
1338-1424 g/mol |
Physical Form or Appearance
|
White or almost white amorphous powder. |
Application |
KLEPTOSE® HPB-LB for parenteral use. It is a pyrogen-free solution that improves drug solubility and stability against light or oxidation by molecular encapsulation. It also reduces irritation at injection site. KLEPTOSE® HPB-LB is a multi-compendial product that complies with European and U.S. Pharmacopeia, and has standards that not only comply with but are even higher than Chinese Pharmacopeia. |
Water Content (LOD) |
Maximum water content: 10 % |
Degree of Substitution |
Molar substitution range: 0.50-0.71 |
Solubility
|
Highly soluble in water. At high concentration, the wetting and dissolution time of the powder is delayed due to its low density and increased viscosity. |
Water sorption isotherm at 20°C |
![]() |
Glass Transition Temperature vs. Water Content |
![]() |
Glass transitiontemperature of the cryo-concentrated phase (Tg’) |
Tg’=-11,1°C
|