White or almost white amorphous powder.
The statistical hydroxypropylation of beta-cyclodextrin creates a multitude of molecules, differing by the position of the hydroxypropyl groups. Consequently, the product is not able to crystallize and remains in the amorphous state.
KLEPTOSE® HPB-LB for parenteral use. It is a pyrogen-free solution that improves drug solubility and stability against light or oxidation by molecular encapsulation. It also reduces irritation at injection site. KLEPTOSE® HPB-LB is a multi-compendial product that complies with European and U.S. Pharmacopeia, and has standards that not only comply with but are even higher than Chinese Pharmacopeia.
Water Content (LOD)
Maximum water content: 10 %
Degree of Substitution
Molar substitution range: 0.50-0.71
Highly soluble in water. At high concentration, the wetting and dissolution time of the powder is delayed due to its low density and increased viscosity.
Soluble in ethanol.
Freely soluble in propylen glycol.
Water sorption isotherm at 20°C
Glass Transition Temperature vs. Water Content
Glass transitiontemperature of the cryo-concentrated phase (Tg’)