KLEPTOSE® HP Biopharma
Hydroxypropyl β-Cyclodextrin - Low endotoxin - High molar substitution
Product Name
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KLEPTOSE® HP Biopharma Low endotoxin Hydroxypropyl β-cyclodextrin |
Generic Name
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HYDROXYPROPYLBETADEX
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CAS Number
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128446-35-5 |
Chemical Structure
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Molecular Weight |
Nominal molecular weight: 1501 g/mol
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Physical Form or Appearence |
White or almost white amorphous powder. |
Application |
KLEPTOSE® HP for biopharma uses. It is a low endotoxin pyrogen-free solution for protein stabilization. It exhibits surface activity and anti-aggregation properties for therapeutic proteins shelf life extension. KLEPTOSE® HP Biopharma also enables to reduce thermal and agitation sensitivity of formulations. |
Water Content (LOD) |
Nominal water content: 4% |
Degree of Substitution |
Nominal molar substitution: 0.9 |
Solubility |
Highly soluble in water. At high concentration, the wetting and dissolution time of the powder is delayed due to its low density and increased viscosity. |
Water sorption isotherm at 20°C |
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Glass transition temperature vs. water content
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Glass transition temperature of the cryo-concentrated phase (Tg’)
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Tg’=-13.5°C
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Viscosity in water
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Surface Tension in Water
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Osmolality
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