KLEPTOSE® HP Biopharma
Hydroxypropyl β-Cyclodextrin - Low endotoxin - High molar substitution

KLEPTOSE® HP Biopharma Low endotoxin Hydroxypropyl β-cyclodextrin

128446-35-5

White or almost white amorphous powder.
The statistical hydroxypropylation of beta-cyclodextrin creates a multitude of molecules, differing by the position of the hydroxypropyl groups. Consequently, the product is not able to crystallize and remains in the amorphous state.

KLEPTOSE® HP for biopharma uses. It is a low endotoxin pyrogen-free solution for protein stabilization. It exhibits surface activity and anti-aggregation properties for therapeutic proteins shelf life extension. KLEPTOSE® HP Biopharma also enables to reduce thermal and agitation sensitivity of formulations.

Nominal water content: 4%
Maximum water content: 10%

Nominal molar substitution: 0.9
Molar substitution range: 0.81-0.99

Highly soluble in water. At high concentration, the wetting and dissolution time of the powder is delayed due to its low density and increased viscosity.
Soluble in ethanol.
Freely soluble in propylen glycol.