KLEPTOSE® DC
β-cyclodextrin
| Product Name | KLEPTOSE® DC |
| Generic Name | Betacyclodextrin |
| Physico-chemical properties | |
| Compliance | EP/USP-NF |
| Synonyms | Beta-cyclodextrin |
| CAS Number | 7585-39-9 |
| Chemical Structure |
|
| Average Molecular Weight | 1135 g/mol |
| Physical Form or Appearence | White or almost white powder |
| Application | KLEPTOSE® DC β-cyclodextrin is a directly compressible excipient for oral dosage forms. It offers solubility increase through molecular encapsulation. |
| Water content (LOD) |
Nominal water content: 12 % Water Content (LOD) Maximum: 14 % |
| Morphology |
|
| Average mean particle diameter | 80 µm |
| Particle Size Distribution by Laser Diffraction |
dv10: 30 µm dv50: 90 µm dv90: 260 µm |
| Solubility | Solubility in water: 18.5 g/l. Practically insoluble in ethanol (95 %) |
| Melting temperature |
Minimum melting temperature : 280 °C Maximum melting temperature: 300 °C |
| Water sorption isotherm at 20°C |
|
| Taste/Odor | Tasteless and odorless |
| Tablet hardness |
|
| Experimental Conditions for Compression Behavior |
Tablet Press: STYL'One Production Speed: simulated rotary press speed: 54000 tablets/hour Tooling: Diameter 11.28 mm flat Formula: External lubrication with magnesium stearate Tablet Mass: 400 mg |
| Powder Characteristics |
Powder Flowability (according to Ph.Eur. 2.9.16, 10mm outflow opening): Need flow aid Bulk Density: 0.55 g/cm3 Tapped Density: 0.77 g/cm3 True Density: 1.48 g/cm3 Specific surface area: 1.31 m2/g |
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® Registered trademark(s) of Roquette Frères. Any information provided herein is intended for healthcare and food industry professionals for internal use only and not to be delivered as such to final consumers. Information is based on our current state of knowledge and made available on an informational basis; products described may have restrictions with respect to their use, communication, and/or usage levels, and such may vary on a country-by-country basis. Manufacturers of dietary supplements should evaluate the intended use of the particular ingredient in their finished dietary supplement to confirm compliance with the applicable laws and regulations of authorities regulating such products, because the suitability and regulatory status of a product may be dependent on its specific intended use. As the use of these products is beyond our control, Roquette makes no express or implied warranties regarding the use of the product and no guarantee of product properties, and in particular no express or implied warranties regarding the use of the product in dietary supplements, including without limitation the implied warranties of merchantability and fitness for a particular purpose, and Roquette disclaims liability for any loss and/or damage related to such use. Roquette, further, does not warrant that the information or its use will not infringe any patent or other proprietary rights of any third party. Roquette providing this information is not a commitment to sell any product encompassing any of such information in the future.