Product Profile
KLEPTOSE® DC
β-cyclodextrin
| Product Name | KLEPTOSE® DC |
| Generic Name | Betacyclodextrin |
| Physico-chemical properties | |
| Compliance | EP/USP-NF |
| Synonyms | Beta-cyclodextrin |
| CAS Number | 7585-39-9 |
| Chemical Structure |
|
| Average Molecular Weight | 1135 g/mol |
| Physical Form or Appearence | White or almost white powder |
| Application | KLEPTOSE® DC β-cyclodextrin is a directly compressible excipient for oral dosage forms. It offers solubility increase through molecular encapsulation. |
| Water content (LOD) |
Nominal water content: 12 % Water Content (LOD) Maximum: 16 % |
| Morphology |
|
| Average mean particle diameter | 80 µm |
| Particle Size Distribution by Laser Diffraction |
dv10: 30 µm dv50: 90 µm dv90: 260 µm |
| Solubility | Solubility in water: 18.5 g/l. Practically insoluble in ethanol (95 %) |
| Melting temperature |
Minimum melting temperature : 280 °C Maximum melting temperature: 300 °C |
| Water sorption isotherm at 20°C |
|
| Taste/Odor | Tasteless and odorless |
| Tablet hardness |
|
| Experimental Conditions for Compression Behavior |
Tablet Press: STYL'One Production Speed: simulated rotary press speed: 54000 tablets/hour Tooling: Diameter 11.28 mm flat Formula: External lubrication with magnesium stearate Tablet Mass: 400 mg |
| Powder Characteristics |
Powder Flowability (according to Ph.Eur. 2.9.16, 10mm outflow opening): Need flow aid Bulk Density: 0.55 g/cm3 Tapped Density: 0.77 g/cm3 True Density: 1.48 g/cm3 Specific surface area: 1.31 m2/g |
Disclaimer
These typical values are provided for information only and we believe them to be reliable. Methods available upon request.