Formulation Guideline
Vitamin C Chewable Tablets Using PEARLITOL® 200 SD Mannitol
Directly compressible formulation for Vitamin C chewable tablets
Formula
|
% (by weight)
|
mg / tablet
|
---|---|---|
PEARLITOL® 200 SD mannitol
|
63.5
|
508.0
|
Ascorbic acid 95% DC (Roche Vitamins)
|
32.9
|
263.2
|
Orange flavor (Firmenich)
|
1.6
|
12.8
|
Magnesium stearate
|
1.5
|
12.0
|
Aspartame
|
0.3
|
2.4
|
Sunset Yellow lake (Sensient)
|
0.2
|
1.6
|
Method
- Mix PEARLITOL® 200 SD, ascorbic acid, aspartame, flavor and color for 5 minutes.
- Add magnesium stearate and mix for 5 minutes.
- Compress the powder with 13 mm concave punches.
Additional comments
- Tablet weight: 800 mg
- Tablet thickness: 6.35 mm
- Tablet density: 1.33 g/cm3
- Tablet hardness: 105 N
- Dosage: 250 mg Vitamin C / 800 mg tablet
Disclaimer
This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s).
These details are for information only and we believe them to be reliable.