Sugar-free Vitamin C Effervescent Tablets Using PEARLITOL® 200 SD Mannitol
Formulation Guideline

Sugar-free Vitamin C Effervescent Tablets Using PEARLITOL® 200 SD Mannitol

Directly compressible formulation for sugar-free vitamin C effervescent tablets

Formula
% (by weight)
mg / tablet
Sodium bicarbonate
30.80
693.00
Tartaric acid
26.40
594.00
Ascorbic acid (90% content) (Hoffmann La Roche)
20.00
450.00
PEARLITOL® 200 SD mannitol
9.44
212.40
Granulated sodium ascorbate (Hoffmann La Roche)
4.70
105.75
Sodium benzoate
3.70
83.25
PEG 6000
2.80
63.00
Orange flavor
1.80
40.50
Sodium saccharinate, ground
0.36
8.10

Method

In a Lödige mixer, pour and mix for 5 minutes in 6 steps:

  1. tartaric acid and sodium bicarbonate
  2. ascorbic acid and sodium ascorbate 
  3. PEARLITOL® 200 SD, flavor and sodium saccharinate
  4. a third of PEG 6000 and sodium benzoate 
  5. a third of PEG 6000 and sodium benzoate
  6. a third of PEG 6000 and sodium benzoate 

The powder is ready to be compressed.

Additional comments

  • 500 mg vitamin C for a 2.25 g tablet.

Disclaimer

This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s). 
These details are for information only and we believe them to be reliable.

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