Multivitamin Chewable Tablets Using PEARLITOL® 200 SD Mannitol

Multivitamin Chewable Tablets Using PEARLITOL® 200 SD Mannitol

Directly compressible formulation for multivitamin chewable tablets


Per tablet
Vitamin A (retinol acetate)

5000 IU

Vitamin D2 (Ergocalciferol)
400 IU
Vitamin E (DL.α.tocopherol acetate)
2 IU
Vitamin C (L (+) Ascorbic acid)
60.0 mg
Vitamin PP (Nicotinamide)
10.0 mg
Vitamin B2 (Riboflavine)
1.5 mg
Vitamin B1 (Thiamin mononitrate)
1.2 mg
Vitamin B6 (Pyridoxine hydrochloride)
1.2 mg
Vitamin H (D (+) Biotin)
40.0 µg
Vitamin B12 (Cyanocobalamin)
3.0 µg
Magnesium stearate
20.0 mg
10.0 mg
Orange powder flavor
6.0 mg
AEROSIL® 200 silica*
1.5 mg
0.4 mg
PEARLITOL® 200 SD mannitol
q.s. 800.0 mg


  1. Dissolve the vitamins A, B12, D2 and E in a sufficient amount of ethanol. 
  2. Spray the solution on the PEARLITOL® 200 SD using a fluidized bed dryer.
  3. Evaporate the alcohol.
  4. Mix all the ingredients except the magnesium stearate for 10 minutes.
  5. Add the magnesium stearate and mix again for 5 minutes.
  6. Compress the powder with 13 mm diameter flat face punches.

Additional Comments

  • Tablet weight: 800 mg
  • Tablet thickness: 5.30 mm
  • Tablet density: 1.137 g/cm3
  •  Tablet hardness: 70 N


This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s). 
These details are for information only and we believe them to be reliable.

*AEROSIL®200 silica is registered trademark of Evonik


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