Formulation Guideline
100 mg Vitamin C Chewable Tablets Using PEARLITOL® 200 SD Mannitol
Directly compressible formulation for 100 mg vitamin C chewable tablets
Formula
|
% (by weight)
|
mg / tablet
|
---|---|---|
PEARLITOL® 200 SD mannitol
|
83.02
|
581.1
|
Ascorbic acid
|
8.57
|
60.0
|
Sodium ascorbate
|
5.71
|
40.0
|
Magnesium stearate
|
1.20
|
8.4
|
Orange powder flavor
|
1.00
|
7.0
|
Aspartame |
0.50
|
3.5
|
Method
- In the mixer, introduce all the ingredients except the lubricant.
- Mix for 5 minutes.
- Add magnesium stearate.
- Mix again for 5 minutes.
- Compress the powder with 13 mm flat face bevel edge punches.
Additional comments
- Tablet weight: 700 mg
- Tablet thickness: 4.36 mm
- Tablet density: 1.204 g/cm3
- Tablet hardness: 80 N
- Dosage: 100 mg vitamin C / 700 mg tablet
Disclaimer
This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s).
These details are for information only and we believe them to be reliable.