PEARLITOL® PRO-TEC - MANNITOL-MAIZE STARCH
PEARLITOL®
®Registered Trademark(s) of Roquette Frères
- Designed for the direct compression of moisture sensitive ingredients.
Low water activity
Low moisture
Applications
- 1. Solid Forms - Tablets
- Swallowable Tablets
- Orally Dispersible Tablets
- Effervescent Tablets
- 5. Other Solid Forms
- Granules and Pellets
Functional properties
- Formulations Aids
- Disintegrants & Super Disintegrants
- Fillers and Binders for Direct Compression
Documents
Product Specification Sheet
Name
Region
Size
Download
PEARLITOL® PROTEC - EXP
473,84 Ko
Region :
473,84 Ko
Safety Data Sheet
Name
Region
Language
Size
Download
PEARLITOL® PROTEC - EXP
Americas, US
EN
269,21 Ko
Region : Americas, US
EN
269,21 Ko
PEARLITOL® PROTEC - EXP
Asia, ID
EN
276,31 Ko
Region : Asia, ID
EN
276,31 Ko
PEARLITOL® PROTEC - EXP
Europe, IT
EN
309,84 Ko
Region : Europe, IT
EN
309,84 Ko
PEARLITOL® PROTEC - EXP
Europe, GB
EN
308,91 Ko
Region : Europe, GB
EN
308,91 Ko
PEARLITOL® PROTEC - EXP
Asia, TW
EN
283,64 Ko
Region : Asia, TW
EN
283,64 Ko
PEARLITOL® PROTEC - EXP
Asia, VN
EN
280,92 Ko
Region : Asia, VN
EN
280,92 Ko
PEARLITOL® PROTEC - EXP
Oceania, AU
EN
275,61 Ko
Region : Oceania, AU
EN
275,61 Ko
PEARLITOL® PROTEC - EXP
Europe, FR
EN
307,68 Ko
Region : Europe, FR
EN
307,68 Ko
PEARLITOL® PROTEC - EXP
Europe, DE
EN
310,22 Ko
Region : Europe, DE
EN
310,22 Ko
PEARLITOL® PROTEC - EXP
Europe, CH
EN
307,66 Ko
Region : Europe, CH
EN
307,66 Ko
PEARLITOL® PROTEC - EXP
Asia, MY
EN
276,50 Ko
Region : Asia, MY
EN
276,50 Ko
PEARLITOL® PROTEC - EXP
Asia, VN
EN
382,42 Ko
Region : Asia, VN
EN
382,42 Ko
PEARLITOL® PROTEC - EXP
Asia, KR
KO
374,09 Ko
Region : Asia, KR
KO
374,09 Ko
PEARLITOL® PROTEC - EXP
Europe, CH
FR
351,58 Ko
Region : Europe, CH
FR
351,58 Ko
PEARLITOL® PROTEC - EXP
Asia, ID
ID
297,56 Ko
Region : Asia, ID
ID
297,56 Ko
PEARLITOL® PROTEC - EXP
Asia, MY
MS
297,68 Ko
Region : Asia, MY
MS
297,68 Ko
PEARLITOL® PROTEC - EXP
Europe, FR
FR
351,07 Ko
Region : Europe, FR
FR
351,07 Ko
PEARLITOL® PROTEC - EXP
Europe, CH
DE
347,30 Ko
Region : Europe, CH
DE
347,30 Ko
PEARLITOL® PROTEC - EXP
Europe, ES
ES
345,55 Ko
Region : Europe, ES
ES
345,55 Ko
PEARLITOL® PROTEC - EXP
Europe, DE
DE
350,87 Ko
Region : Europe, DE
DE
350,87 Ko
PEARLITOL® PROTEC - EXP
Americas, BR
PT
348,60 Ko
Region : Americas, BR
PT
348,60 Ko
PEARLITOL® PROTEC - EXP
Europe, CH
IT
340,94 Ko
Region : Europe, CH
IT
340,94 Ko
PEARLITOL® PROTEC - EXP
Asia, TH
TH
367,21 Ko
Region : Asia, TH
TH
367,21 Ko
PEARLITOL® PROTEC - EXP
Europe, IT
IT
343,12 Ko
Region : Europe, IT
IT
343,12 Ko
Get in touch with our Technical Experts
Please feel free to contact our technical experts for support during the development process.
Technical data
| Synonyms | D-Mannitol-Starch |
|---|---|
| Composition | Approximately D-Mannitol 80%-Dehydrated Extra White Maize Starch 20% |
| CAS number | D-Mannitol 69-65-8Maize Starch 9005-25-8 |
| Physical form or apperance | White powder |
| Application | PEARLITOL® ProTec co-processed mannitol-starch is designed for the direct compression of moisture\nsensitive ingredients such as probiotics and vitamins. PEARLITOL® ProTec provides protection from\ntableting process, including compression and improves stability due to low-water activity. PEARLITOL® ProTec may also be used in free-flowing powder formulations such as stick packs and sachets. |
| Teste/Odor | Slightly sweet |
| Morphology |
|
| Water sorption isotherm at 20°C |
|
| Chemical Structure |
|
| Average molecular weight | Mannitol: 182.2 g/mol |
| Maximal Water content (LOD) | 1.00 |
| Solubility | Partially soluble in cold water, practically insoluble in ethanol (96%) |
| Minimum melting temperature | Mannitol: 165 °C |
| Maximum melting temperature | Mannitol: 170 °C |
| Water Activity | 0.20 |
| Average mean particle diameter | 120 |
| dv10 Particle size distribution | 50 |
| dv50 Particle size distribution | 120 |
| dv90 Particle size distribution | 200 |
| Tablet Hardness |
|
| Experimental Conditions for Compression Behavior_Tablet Press | STYL'ONE EVO |
| Experimental Conditions for Compression Behavior_Production Speed | 25, 40 and 60 RPM (linear punch velocity: 35, 56 and 84 mm/s; simulated KORSCH XL-400 rotary press speed: 52,500, 84,000 and 126,000 tablets/hour) |
| Experimental Conditions for Compression Behavior_Tooling | Diameter 10 mm R10 concave |
| Experimental Conditions for Compression Behavior_Formuls | 98.8% PEARLITOL® ProTec / 1.2% magnesium stearate |
| Experimental Conditions for Compression Behavior_Tablet Mass | 400 mg |
| Powder Flowability (according to Ph.Eur. 2.9.16, 10mm outflow opening) | 5 |
| Bulk Density (g/ml) | 0.48 |
| Tapped Density (g/ml) | 0.56 |
| True Density (g/ml) | 1.44 |
| Specific Surface Area (m²/g) | 1.60 |
| Angle of Repose (°) | 30 |