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NEOSORB® P 650 DC - SORBITOL

NEOSORB®

®Registered Trademark(s) of Roquette Frères
  • Spray dried
  • mean diameter of 650 µm

Sorbitol powder

Applications

  • 1. Solid Forms - Tablets
  • Chewable Tablets
  • Swallowable Tablets
  • Effervescent Tablets
  • 2. Solid Forms - Capsules
  • Hard Capsules Fill
  • 5. Other Solid Forms
  • Losenges
  • Medicated Confectionaries
  • Stick Packs and sachets
  • 3. Films and coatings
  • Film Coating
  • 4. Liquid Forms
  • Creams | Pastes & Semi-Solids

Functional properties

  • Formulations Aids
  • Fillers and Binders for Direct Compression
  • Fillers and Binders for Roller Compaction
  • Humectants
  • Sensory Enhancers
  • Sweetening agent
  • Stabilizers and Adjusters
  • Plasticizers

Physical and chemical properties

  • Health & Nutritional Benefits
  • Sugar-free
  • Gluten-free
  • Non-cariogenic
  • General Properties
  • Label-friendly
  • Multicompendial

Documents

Product Specification Sheet

Region :

494,51 Ko

Safety Data Sheet

Region : Oceania, AU

EN 272,93 Ko

Region : Europe, BE

EN 519,21 Ko

Region : Europe, CH

EN 519,37 Ko

Region : Europe, DE

EN 521,92 Ko

Region : Europe, FR

EN 519,29 Ko

Region : Europe, GB

EN 381,63 Ko

Region : Americas, Asia, Oceania, Africa

EN 271,06 Ko

Region : Asia, IN

EN 270,94 Ko

Region : Europe, AT

DE 531,63 Ko

Region : Europe, BE

DE 531,49 Ko

Region : Europe, BE

FR 632,86 Ko

Region : Europe, BE

NL 527,50 Ko

Region : Americas, BR

PT 537,30 Ko

Region : Europe, CH

DE 531,71 Ko

Region : Europe, CH

FR 633,31 Ko

Region : Europe, CH

IT 621,44 Ko

Region : Europe, CZ

CS 653,09 Ko

Region : Europe, DE

DE 536,25 Ko

Region : Europe, ES

ES 534,18 Ko

Region : Europe, DK

DA 528,83 Ko

Region : Europe, FR

FR 633,06 Ko

Region : Americas, Asia, Oceania, Africa

ES 285,16 Ko

Region : Americas, Asia, Oceania, Africa

PT 290,58 Ko

Region : Americas, Asia, Oceania, Africa

RU 418,14 Ko

Region : Europe, GR

EL 673,61 Ko

Get in touch with our Technical Experts

Please feel free to contact our technical experts for support during the development process.

Technical data

Synonyms D-Glucitol
CAS number 50-70-4
Physical form or apperance White or almost white crystalline powder
Application NEOSORB® P 650 DC sorbitol is a direct compression excipient. It is a non-cariogenic and non-acidogenic sugar-free sweetener that is suitable for chewable, suckable or effervescent tablets.
Teste/Odor Slightly sweet (sweetening power about 50-60% that of sucrose) with cooling effect due to high dissolution enthalpy in water (111 J/g)
Morphology
MORPHOLOGY
Water sorption isotherm at 20°C
WATER_SORPTION
Chemical Structure
CHEMICAL_STRUCTURE
Average molecular weight 182.2 g/mol
Nominal Water content (LOD) 0.30
Maximal Water content (LOD) 1.50
Solubility Very soluble in water (235 g/100 ml of water at 25°C), practically insoluble in ethanol (96%)
Minimum melting temperature 95 °C
Maximum melting temperature 98 °C
Average mean particle diameter 650
dv10 Particle size distribution 490
dv50 Particle size distribution 770
dv90 Particle size distribution 1100
Tablet Hardness
COMPRESSION_BEHAVIOUR_TABLET_HARDNESS
Experimental Conditions for Compression Behavior_Tablet Press STYLCAM 200R
Experimental Conditions for Compression Behavior_Production Speed 10, 25 and 40 tablets/min (respective linear punch velocity: 38, 96 and 152 mm/s ; respective simulated rotary press speed: 60000, 150000 and 250000 tablets/hour)
Experimental Conditions for Compression Behavior_Tooling Diameter 10 mm R9 concave
Experimental Conditions for Compression Behavior_Formuls 99.3% NEOSORB® P 650 DC / 0.7% magnesium stearate
Experimental Conditions for Compression Behavior_Tablet Mass 400 mg
Powder Flowability (according to Ph.Eur. 2.9.16, 10mm outflow opening) 11
Bulk Density (g/ml) 0.59
Tapped Density (g/ml) 0.70
True Density (g/ml) 1.51
Specific Surface Area (m²/g) 1.55
Angle of Repose (°) 32