Dosage Accuracy and Consistency
Precise dosage and consistent tablet performance are critical for safety, therapeutic success, and compliance. Roquette’s range of pharmaceutical fillers, diluents, and binders is engineered to support accurate tablet weight, uniform active pharmaceutical ingredient (API) distribution, and reproducible release profiles.
Pharmaceutical Fillers, Diluents, and Binders
Our excipients provide robust performance across multiple manufacturing processes, including direct compression and wet granulation, while enhancing patient compliance with superior taste, mouthfeel, and swallowability of chewables, orally disintegrating tablets (ODTs), and effervescents. Combined with our advanced quality systems, global regulatory compliance, and technical support, Roquette ensures confidence in formulation reproducibility from laboratory scale through full-scale production.
Our Solutions
Roquette excipients address formulation challenges by ensuring dosage accuracy, reproducibility, and patient acceptability. Each category of solution contributes to reliable tablet and capsule performance.
Fillers
Fillers such as mannitol, sorbitol, maltitol, and xylitol enable uniform blending and precise weight per dose. These excipients support consistent API distribution and reproducible tablet performance. They are ideal for chewables, effervescents, and swallowable tablets.
Binders
Binders including LYCATAB® PGS pregelatinized maize starch and LYCATAB® DSH maize maltodextrin provide tablet strength and batch-to-batch consistency, resulting in consistent granule quality and robust tablet strength. They are key to maintaining reproducibility across batches.
Co-Processed Excipients
Products like StarLac® co-processed lactose-starch and PEARLITOL® Flash co-processed mannitol-starch combine filler and binder functionality, delivering reliable compressibility and disintegration with low variability for direct compression and chewable formulations. They are designed to improve mouthfeel and disintegration in ODTs and chewables.
Microcrystalline Cellulose (MCC)
MICROCEL® microcrystalline cellulose is a global standard excipient with wide pharmacopeial recognition. MCC ensures batch-to-batch reproducibility and stability, supporting tablet and capsule integrity from laboratory trials to commercial production.
Polyols
Polyols such as SweetPearl® maltitol powder, NEOSORB® sorbitol, and XYLISORB® xylitol provide consistent performance in chewables and ODTs. They enhance taste and mouthfeel with sugar-free and non-cariogenic properties, contributing to patient compliance.
Our Services and Expertise
At Roquette, dosage accuracy and reproducibility are supported not only by high-quality excipients but also by the services and expertise surrounding them. Our Customer Technical Services (CTS) laboratories support scale-up of ODTs by working directly with formulation teams to replicate manufacturing conditions, ensuring consistent hardness and friability.
Global regulatory compliance and robust quality systems, including EXCiPACT certification, give customers confidence that Roquette excipients will meet international standards. Backed by decades of experience in starch and polyol technologies, Roquette provides trusted solutions that combine technical reliability, regulatory assurance, and patient-focused innovation. All of our solutions are based on plant-derived raw materials, supporting sustainability goals.
Key Roquette Fillers, Binders, and Diluents
Our portfolio of high-quality excipients is designed for precise dosage, reproducible performance, and patient-friendly formulations. Each product delivers unique functionality to meet the demands of modern pharmaceutical manufacturing.