Vitamin E Chewable Tablets Using PEARLITOL® 200 SD Mannitol and XYLISORB® 300 Xylitol
Published January 27, 2026
Resource
Pharma
Directly compressible formulation for vitamin E chewable tablets
Formula
| % (by weight) | mg / tablet | |
|---|---|---|
| PEARLITOL® 200 SD mannitol | 43.93 | 659.0 |
| XYLISORB® 300 xylitol | 43.93 | 659.0 |
| KLEPTOSE® βCD beta-cyclodextrin | 7.67 | 115.0 |
| DLα tocopherol acetate | 1.67 | 25.0 |
| Magnesium stearate | 1.50 | 22.5 |
| Mint flavor (Firmenich) | 0.60 | 9.0 |
| Citric acid | 0.40 | 6.0 |
| Lemon flavor (Firmenich) | 0.30 | 4.5 |
Method
- Mix KLEPTOSE® βCD and water into a double jacket mixer heated to 50°C.
- Introduce tocopherol acetate and mix for 2 hours.
- Dry the mix in a drying oven at 45°C.
- Grind the dry complex KLEPTOSE® βCD / tocopherol acetate.
- Mix PEARLITOL® 200 SD, XYLISORB® 300, dry complex, citric acid and flavors for 5 minutes.
- Add magnesium stearate and mix for 5 minutes.
- Compress the powder with 18 mm flat face punches.
Additional comments
- Tablet weight: 1500 mg
- Tablet thickness: 4.70 mm
- Tablet density: 1.25 g/cm3
- Tablet hardness: 80 N
- Dosage: 25 mg vitamin E / 1500 mg tablet
Disclaimer
This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s).
These details are for information only and we believe them to be reliable.