Sugar-free Vitamin C Effervescent Tablets Using PEARLITOL® 200 SD Mannitol
Published January 27, 2026
Resource
Pharma
Directly compressible formulation for sugar-free vitamin C effervescent tablets
Formula
| % (by weight) | mg / tablet | |
|---|---|---|
| Sodium bicarbonate | 30.80 | 693.00 |
| Tartaric acid | 26.40 | 594.00 |
| Ascorbic acid (90% content) (Hoffmann La Roche) | 20.00 | 450.00 |
| PEARLITOL® 200 SD mannitol | 9.44 | 212.40 |
| Granulated sodium ascorbate (Hoffmann La Roche) | 4.70 | 105.75 |
| Sodium benzoate | 3.70 | 83.25 |
| PEG 6000 | 2.80 | 63.00 |
| Orange flavor | 1.80 | 40.50 |
| Sodium saccharinate, ground | 0.36 | 8.10 |
Method
In a Lödige mixer, pour and mix for 5 minutes in 6 steps:
- tartaric acid and sodium bicarbonate
- ascorbic acid and sodium ascorbate
- PEARLITOL® 200 SD, flavor and sodium saccharinate
- a third of PEG 6000 and sodium benzoate
- a third of PEG 6000 and sodium benzoate
- a third of PEG 6000 and sodium benzoate
The powder is ready to be compressed.
Additional comments
- 500 mg vitamin C for a 2.25 g tablet.
Disclaimer
This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s).
These details are for information only and we believe them to be reliable.