Sugar-free Antacid Chewable Tablets Using PEARLITOL® 200 SD Mannitol
Published January 27, 2026
Resource
Pharma
Directly compressible formulation for sugar-free antacid chewable tablets
Formula
| % (by weight) | mg / tablet | |
|---|---|---|
| PEARLITOL® 200 SD mannitol | 71.7 | 573.6 |
| Aluminium hydroxide | 20.0 | 160.0 |
| Magnesium hydroxide | 5.0 | 40.0 |
| Magnesium stearate | 2.0 | 16.0 |
| Buttermint flavor | 1.0 | 8.0 |
| AEROSIL® R972 silica* | 0.3 | 2.4 |
Method
- Mix aluminium hydroxide, magnesium hydroxide and silica in the mixer for 5 minutes.
- Add the flavor and PEARLITOL® 200 SD and mix again for 5 minutes.
- Add the magnesium stearate and mix for 5 minutes.
- Compress the powder with 13 mm round flat face punches.
Additional comments
- Tablet weight: 800 mg
- Tablet thickness: 4.40 mm
- Tablet density: 1.373 g/cm3
- Tablet hardness: 80 N
Disclaimer
This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s).
These details are for information only and we believe them to be reliable.
*AEROSIL®R972 is registered trademark of Evonik