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Placebo Swallowable Tablets Using PEARLITOL® 200 SD Mannitol and GLYCOLYS® Sodium Starch Glycolate

Published January 28, 2026

Resource Pharma

Directly compressible formulation for placebo swallowable tablets

tablet.jpg

Formula

 % (by weight)mg / tablet
PEARLITOL® 200 SD mannitol95.5310.4
GLYCOLYS® sodium starch glycolate3.09.7
Magnesium stearate1.54.8

Method

  1. In a mixer, mix PEARLITOL® 200 SD and GLYCOLYS® for 5 minutes.
  2. Add magnesium stearate and mix for 5 minutes.
  3. Compress the powder with 10 mm concave punches.

Additional comments

  • Tablet weight: 325 mg
  • Tablet thickness: 5.0 mm
  • Tablet hardness: 75 N
  • In vitro tablet disintegration time: 55 s

Disclaimer

This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s). 
These details are for information only and we believe them to be reliable.