Placebo Swallowable Tablets Using PEARLITOL® 200 SD Mannitol and GLYCOLYS® Sodium Starch Glycolate
Published January 28, 2026
Resource
Pharma
Directly compressible formulation for placebo swallowable tablets

Formula
| % (by weight) | mg / tablet | |
|---|---|---|
| PEARLITOL® 200 SD mannitol | 95.5 | 310.4 |
| GLYCOLYS® sodium starch glycolate | 3.0 | 9.7 |
| Magnesium stearate | 1.5 | 4.8 |
Method
- In a mixer, mix PEARLITOL® 200 SD and GLYCOLYS® for 5 minutes.
- Add magnesium stearate and mix for 5 minutes.
- Compress the powder with 10 mm concave punches.
Additional comments
- Tablet weight: 325 mg
- Tablet thickness: 5.0 mm
- Tablet hardness: 75 N
- In vitro tablet disintegration time: 55 s
Disclaimer
This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s).
These details are for information only and we believe them to be reliable.