Placebo Soft Chewable Tablets Using PEARLITOL® 200 SD Mannitol
Published January 27, 2026
Resource
Pharma
Directly compressible formulation for placebo soft chewable tablets
Formula
| % (by weight) | mg / tablet | |
|---|---|---|
| PEARLITOL® 200 SD mannitol | 97.18 | 655.97 |
| Powdered mint flavor (Givaudan) | 1.00 | 6.75 |
| Aspartame | 0.30 | 2.02 |
| Eurolake Patent Blue V (Sensient) | 0.02 | 0.14 |
| Magnesium stearate | 1.50 | 10.12 |
Method
- In a mixer, mix PEARLITOL® 200 SD, flavor, lake and aspartame for 10 minutes.
- Add magnesium stearate and mix for 5 minutes.
- Compress the powder with 13 mm flat face bevel edge punches.
Additional comments
- Tablet weight: 675 mg
- Tablet thickness: 4.5 mm
- Tablet density: 1.126 g/cm3
- Tablet hardness: 80 N
Disclaimer
This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s).
These details are for information only and we believe them to be reliable.