Placebo Orodispersible Tablets using PEARLITOL® Flash Mannitol-Maize Starch Compound
Published January 27, 2026
Resource
Pharma
Placebo formulation for a directly compressible mint flavor orodispersible tablets (ODT)
Formula
| % (By weight) | mg / tablet | |
|---|---|---|
| PEARLITOL® Flash mannitol, starch | 98.3 | 491.5 |
| Mint flavor powder | 1.0 | 5.0 |
| Aspartame | 0.3 | 1.5 |
| Magnesium stearate | 0.4 | 2.0 |
Method
- In a mixer, mix PEARLITOL® Flash, mint flavor and aspartame for 5 minutes.
- Add magnesium stearate and mix for 5 minutes.
- Compress the powder with 13 mm flat face bevel edge punches.
Additional comments
- Tablet weight: 499.1 mg
- Tablet thickness: 3.0 mm
- Tablet density: 1.253 g/cm3
- Tablet hardness: 74 N
- In vivo disintegration time: 35 s
Disclaimer
This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s).
These details are for information only and we believe them to be reliable.