NEOSORB® P 300 SD - SORBITOL
NEOSORB®
®Registered Trademark(s) of Roquette Frères
- Designed for direct compression
- Optimized to absorb liquid
Particle size mean diameter - 300 µm approx
Applications
- 1. Solid Forms - Tablets
- Chewable Tablets
- Swallowable Tablets
- Effervescent Tablets
- 2. Solid Forms - Capsules
- Hard Capsules Fill
- 5. Other Solid Forms
- Losenges
- Medicated Confectionaries
- Stick Packs and sachets
- 3. Films and coatings
- Film Coating
- 4. Liquid Forms
- Creams | Pastes & Semi-Solids
Functional properties
- Formulations Aids
- Fillers and Binders for Direct Compression
- Fillers and Binders for Roller Compaction
- Humectants
- Sensory Enhancers
- Sweetening agent
- Stabilizers and Adjusters
- Plasticizers
Physical and chemical properties
- Health & Nutritional Benefits
- Sugar-free
- Gluten-free
- Non-cariogenic
- General Properties
- Label-friendly
- Multicompendial
Documents
Product Specification Sheet
Name
Region
Size
Download
NEOSORB® P300 SD
481,62 Ko
Region :
481,62 Ko
NEOSORB® P300 SD
490,11 Ko
Region :
490,11 Ko
Safety Data Sheet
Name
Region
Language
Size
Download
NEOSORB® P300 SD
Oceania, AU
EN
276,09 Ko
Region : Oceania, AU
EN
276,09 Ko
NEOSORB® P300 SD
Europe, BE
EN
522,11 Ko
Region : Europe, BE
EN
522,11 Ko
NEOSORB® P300 SD
Americas, CA
EN
283,07 Ko
Region : Americas, CA
EN
283,07 Ko
NEOSORB® P300 SD
Europe, CH
EN
522,23 Ko
Region : Europe, CH
EN
522,23 Ko
NEOSORB® P300 SD
Europe, CY
EN
519,07 Ko
Region : Europe, CY
EN
519,07 Ko
NEOSORB® P300 SD
Europe, DE
EN
524,87 Ko
Region : Europe, DE
EN
524,87 Ko
NEOSORB® P300 SD
Europe, FR
EN
522,17 Ko
Region : Europe, FR
EN
522,17 Ko
NEOSORB® P300 SD
Europe, GB
EN
384,58 Ko
Region : Europe, GB
EN
384,58 Ko
NEOSORB® P300 SD
Americas, Asia, Oceania, Africa
EN
274,81 Ko
Region : Americas, Asia, Oceania, Africa
EN
274,81 Ko
NEOSORB® P300 SD
Europe, AT
DE
534,18 Ko
Region : Europe, AT
DE
534,18 Ko
NEOSORB® P300 SD
Europe, BE
DE
534,48 Ko
Region : Europe, BE
DE
534,48 Ko
NEOSORB® P300 SD
Europe, BE
FR
636,04 Ko
Region : Europe, BE
FR
636,04 Ko
NEOSORB® P300 SD
Europe, BE
NL
530,49 Ko
Region : Europe, BE
NL
530,49 Ko
NEOSORB® P300 SD
Americas, CA
FR
398,13 Ko
Region : Americas, CA
FR
398,13 Ko
NEOSORB® P300 SD
Europe, CH
DE
534,71 Ko
Region : Europe, CH
DE
534,71 Ko
NEOSORB® P300 SD
Europe, CH
FR
636,43 Ko
Region : Europe, CH
FR
636,43 Ko
NEOSORB® P300 SD
Europe, CH
IT
624,39 Ko
Region : Europe, CH
IT
624,39 Ko
NEOSORB® P300 SD
Europe, CY
EL
676,50 Ko
Region : Europe, CY
EL
676,50 Ko
NEOSORB® P300 SD
Europe, CY
TR
640,71 Ko
Region : Europe, CY
TR
640,71 Ko
NEOSORB® P300 SD
Europe, CZ
CS
656,00 Ko
Region : Europe, CZ
CS
656,00 Ko
NEOSORB® P300 SD
Europe, DE
DE
539,08 Ko
Region : Europe, DE
DE
539,08 Ko
NEOSORB® P300 SD
Europe, ES
ES
537,15 Ko
Region : Europe, ES
ES
537,15 Ko
NEOSORB® P300 SD
Europe, FR
FR
636,19 Ko
Region : Europe, FR
FR
636,19 Ko
NEOSORB® P300 SD
Americas, Asia, Oceania, Africa
ES
288,96 Ko
Region : Americas, Asia, Oceania, Africa
ES
288,96 Ko
NEOSORB® P300 SD
Americas, Asia, Oceania, Africa
PT
293,89 Ko
Region : Americas, Asia, Oceania, Africa
PT
293,89 Ko
Get in touch with our Technical Experts
Please feel free to contact our technical experts for support during the development process.
Technical data
| Synonyms | D-Glucitol |
|---|---|
| CAS number | 50-70-4 |
| Physical form or apperance | White or almost white crystalline powder |
| Application | NEOSORB® P 300 SD sorbitol is a direct compression excipient. It is a non-cariogenic and non-acidogenic sugar-free sweetener that is suitable for chewable, suckable or effervescent tablets. |
| Teste/Odor | Slightly sweet (sweetening power about 50-60% that of sucrose) with cooling effect due to high dissolution enthalpy in water (111 J/g) |
| Morphology |
|
| Water sorption isotherm at 20°C |
|
| Chemical Structure |
|
| Average molecular weight | 182.2 g/mol |
| Nominal Water content (LOD) | 0.50 |
| Maximal Water content (LOD) | 1.50 |
| Solubility | Very soluble in water (235 g/100 ml of water at 25°C), practically insoluble in ethanol (96%) |
| Minimum melting temperature | 95 °C |
| Maximum melting temperature | 98 °C |
| Average mean particle diameter | 300 |
| dv10 Particle size distribution | 156 |
| dv50 Particle size distribution | 304 |
| dv90 Particle size distribution | 530 |
| Tablet Hardness |
|
| Experimental Conditions for Compression Behavior_Tablet Press | STYLCAM 200R |
| Experimental Conditions for Compression Behavior_Production Speed | 25 tablets/min (linear punch velocity: 96 mm/s; simulated rotary press speed: approximately 150000 tablets/hour) |
| Experimental Conditions for Compression Behavior_Tooling | Diameter 10 mm R9 concave |
| Experimental Conditions for Compression Behavior_Formuls | 99.5% NEOSORB® P 300 SD / 0.5% magnesium stearate |
| Experimental Conditions for Compression Behavior_Tablet Mass | 400 mg |
| Powder Flowability (according to Ph.Eur. 2.9.16, 10mm outflow opening) | 7 |
| Bulk Density (g/ml) | 0.53 |
| Tapped Density (g/ml) | 0.57 |
| True Density (g/ml) | 1.51 |
| Specific Surface Area (m²/g) | 2.10 |
| Angle of Repose (°) | 32 |