PEARLITOL® FLASH - MANNITOL
PEARLITOL®
®Registered Trademark(s) of Roquette Frères
- Optimized for the direct compression of fast oral disintegration tablets with pleasant taste and texture.
Co-processed mannitol starch. Can be supplied with food grade documentation for nutraceuticals.
Applications
- 1. Solid Forms - Tablets
- Orally Dispersible Tablets
Functional properties
- Formulations Aids
- Disintegrants & Super Disintegrants
- Fillers and Binders for Direct Compression
Physical and chemical properties
- General Properties
- Available with Food Grade for Nutraceuticals (some regions)
Documents
Safety Data Sheet
Name
Region
Language
Size
Download
PEARLITOL® FLASH-MANNITOL
Oceania, AU
EN
267,27 Ko
Region : Oceania, AU
EN
267,27 Ko
PEARLITOL® FLASH-MANNITOL
Europe, BE
EN
525,59 Ko
Region : Europe, BE
EN
525,59 Ko
PEARLITOL® FLASH-MANNITOL
Americas, CA
EN
279,56 Ko
Region : Americas, CA
EN
279,56 Ko
PEARLITOL® FLASH-MANNITOL
Europe, CH
EN
525,88 Ko
Region : Europe, CH
EN
525,88 Ko
PEARLITOL® FLASH-MANNITOL
Asia, CN
EN
321,06 Ko
Region : Asia, CN
EN
321,06 Ko
PEARLITOL® FLASH-MANNITOL
Europe, DE
EN
528,78 Ko
Region : Europe, DE
EN
528,78 Ko
PEARLITOL® FLASH-MANNITOL
Europe, FI
EN
525,63 Ko
Region : Europe, FI
EN
525,63 Ko
PEARLITOL® FLASH-MANNITOL
Europe, FR
EN
525,81 Ko
Region : Europe, FR
EN
525,81 Ko
PEARLITOL® FLASH-MANNITOL
Europe, GB
EN
386,93 Ko
Region : Europe, GB
EN
386,93 Ko
PEARLITOL® FLASH-MANNITOL
Europe, AT
DE
543,97 Ko
Region : Europe, AT
DE
543,97 Ko
PEARLITOL® FLASH-MANNITOL
Europe, BE
DE
543,73 Ko
Region : Europe, BE
DE
543,73 Ko
PEARLITOL® FLASH-MANNITOL
Europe, BE
FR
640,31 Ko
Region : Europe, BE
FR
640,31 Ko
PEARLITOL® FLASH-MANNITOL
Europe, BE
NL
537,16 Ko
Region : Europe, BE
NL
537,16 Ko
PEARLITOL® FLASH-MANNITOL
Americas, BR
PT
531,17 Ko
Region : Americas, BR
PT
531,17 Ko
PEARLITOL® FLASH-MANNITOL
Americas, CA
FR
393,73 Ko
Region : Americas, CA
FR
393,73 Ko
PEARLITOL® FLASH-MANNITOL
Europe, CH
DE
544,09 Ko
Region : Europe, CH
DE
544,09 Ko
PEARLITOL® FLASH-MANNITOL
Europe, CH
FR
640,47 Ko
Region : Europe, CH
FR
640,47 Ko
PEARLITOL® FLASH-MANNITOL
Europe, CH
IT
629,85 Ko
Region : Europe, CH
IT
629,85 Ko
PEARLITOL® FLASH-MANNITOL
Asia, CN
ZH
633,98 Ko
Region : Asia, CN
ZH
633,98 Ko
PEARLITOL® FLASH-MANNITOL
Europe, CZ
CS
661,46 Ko
Region : Europe, CZ
CS
661,46 Ko
PEARLITOL® FLASH-MANNITOL
Europe, DE
DE
546,99 Ko
Region : Europe, DE
DE
546,99 Ko
PEARLITOL® FLASH-MANNITOL
Europe, DK
DA
536,18 Ko
Region : Europe, DK
DA
536,18 Ko
PEARLITOL® FLASH-MANNITOL
Europe, ES
ES
540,17 Ko
Region : Europe, ES
ES
540,17 Ko
PEARLITOL® FLASH-MANNITOL
Europe, FI
FI
542,00 Ko
Region : Europe, FI
FI
542,00 Ko
PEARLITOL® FLASH-MANNITOL
Europe, FR
FR
640,56 Ko
Region : Europe, FR
FR
640,56 Ko
Get in touch with our Technical Experts
Please feel free to contact our technical experts for support during the development process.
Technical data
| Synonyms | D-Mannitol-Starch |
|---|---|
| Composition | Approximately D-Mannitol 80%-Extra White Maize Starch 20% |
| CAS number | D-Mannitol 69-65-8Maize Starch 9005-25-8 |
| Physical form or apperance | White powder |
| Application | PEARLITOL® Flash co-processed mannitol-starch is a direct compression excipient with disintegrant properties. It offers excellent chemical inertness and consistent rapid disintegration time. It brings a pleasant taste and texture and is suitable for swallowable and orally dispersible tablets. |
| Teste/Odor | Slightly sweet |
| Morphology |
|
| Water sorption isotherm at 20°C |
|
| Chemical Structure |
|
| Average molecular weight | Mannitol: 182.2 g/mol |
| Maximal Water content (LOD) | 3.00 |
| Solubility | Partially soluble in cold water, practically insoluble in ethanol (96%) |
| Minimum melting temperature | Mannitol: 165 °C |
| Maximum melting temperature | Mannitol: 170 °C |
| Average mean particle diameter | 200 |
| dv10 Particle size distribution | 80 |
| dv50 Particle size distribution | 200 |
| dv90 Particle size distribution | 300 |
| Tablet Hardness |
|
| Experimental Conditions for Compression Behavior_Tablet Press | STYLCAM 200R |
| Experimental Conditions for Compression Behavior_Production Speed | 10 tabs/min (linear punch velocity: 38 mm/s ; simulated rotary press speed: 60000 tablets/hour) |
| Experimental Conditions for Compression Behavior_Tooling | Diameter 10 mm flat |
| Experimental Conditions for Compression Behavior_Formuls | 98.8% PEARLITOL® Flash / 1.2% magnesium stearate |
| Powder Flowability (according to Ph.Eur. 2.9.16, 10mm outflow opening) | 5 |
| Bulk Density (g/ml) | 0.52 |
| Tapped Density (g/ml) | 0.65 |
| True Density (g/ml) | 1.50 |
| Specific Surface Area (m²/g) | 0.55 |
| Angle of Repose (°) | 29 |