KLEPTOSE® HP ORAL - HYDROXYPROPYLBETADEX
KLEPTOSE®
®Registered Trademark(s) of Roquette Frères
- Molecular encapsulation
- Improve API solubility and/or stability
High molecular substitution (MS) = 0.9
Applications
- 1. Solid Forms - Tablets
- Chewable Tablets
- Swallowable Tablets
- Effervescent Tablets
- 2. Solid Forms - Capsules
- Hard Capsules Shell
- 5. Other Solid Forms
- Losenges
- Medicated Confectionaries
- Granules and Pellets
- 3. Films and coatings
- Orally Dissolving Films
- 4. Liquid Forms
- Creams | Pastes & Semi-Solids
- Syrups | Suspensions and Liquids
Functional properties
- Sensory Enhancers
- Taste and odor masking agents
- Stabilizers and Adjusters
- Complexing Agents
- Stabilizers
Documents
Product Specification Sheet
Name
Region
Size
Download
KLEPTOSE® HP ORAL GRADE EP-USP
481,62 Ko
Region :
481,62 Ko
Safety Data Sheet
Name
Region
Language
Size
Download
KLEPTOSE® HP ORAL GRADE EP-USP
Oceania, AU
EN
263,24 Ko
Region : Oceania, AU
EN
263,24 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, BE
EN
509,13 Ko
Region : Europe, BE
EN
509,13 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, CH
EN
509,53 Ko
Region : Europe, CH
EN
509,53 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, DE
EN
512,25 Ko
Region : Europe, DE
EN
512,25 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, FR
EN
509,47 Ko
Region : Europe, FR
EN
509,47 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, GB
EN
372,89 Ko
Region : Europe, GB
EN
372,89 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Americas, Asia, Oceania, Africa
EN
264,34 Ko
Region : Americas, Asia, Oceania, Africa
EN
264,34 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Americas, Asia, Oceania, Africa
EN
275,52 Ko
Region : Americas, Asia, Oceania, Africa
EN
275,52 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, IT
EN
515,06 Ko
Region : Europe, IT
EN
515,06 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, IT
EN
615,92 Ko
Region : Europe, IT
EN
615,92 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Asia, ID
EN
264,06 Ko
Region : Asia, ID
EN
264,06 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, NL
EN
509,27 Ko
Region : Europe, NL
EN
509,27 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, BE
DE
523,31 Ko
Region : Europe, BE
DE
523,31 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, BE
FR
621,51 Ko
Region : Europe, BE
FR
621,51 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, BE
NL
517,18 Ko
Region : Europe, BE
NL
517,18 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Americas, BR
PT
528,71 Ko
Region : Americas, BR
PT
528,71 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, CH
DE
521,38 Ko
Region : Europe, CH
DE
521,38 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, CH
FR
623,96 Ko
Region : Europe, CH
FR
623,96 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, CH
IT
609,38 Ko
Region : Europe, CH
IT
609,38 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, DE
DE
526,09 Ko
Region : Europe, DE
DE
526,09 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, ES
ES
524,03 Ko
Region : Europe, ES
ES
524,03 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Europe, FR
FR
624,48 Ko
Region : Europe, FR
FR
624,48 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Americas, Asia, Oceania, Africa
PT
278,25 Ko
Region : Americas, Asia, Oceania, Africa
PT
278,25 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Americas, Asia, Oceania, Africa
RU
405,03 Ko
Region : Americas, Asia, Oceania, Africa
RU
405,03 Ko
KLEPTOSE® HP ORAL GRADE EP-USP
Asia, ID
ID
270,93 Ko
Region : Asia, ID
ID
270,93 Ko
Get in touch with our Technical Experts
Please feel free to contact our technical experts for support during the development process.
Technical data
| Synonyms | HYDROXYPROPYLBETADEX |
|---|---|
| CAS number | 128446-35-5 |
| Physical form or apperance | White or almost white amorphous powder. The statistical hydroxypropylation of beta-cyclodextrin creates a multitude of molecules, differing by the position of the hydroxypropyl groups. Consequently, the product is not able to crystallize and remains in the amorphous state |
| Application | KLEPTOSE® HP oral hydroxypropyl β-cyclodextrin use is limited to oral dosage forms. It offers taste masking and solubility increase through molecular encapsulation. |
| Teste/Odor | Slightly sweet |
| Morphology |
|
| Water sorption isotherm at 20°C |
|
| Chemical Structure |
|
| Glass Transition Temperature vs. Water Content |
|
| Viscosity in water at 2°C |
|
| Surface Tension |
|
| Osmolality |
|
| Average molecular weight | 1501 g/mol |
| Nominal Water content (LOD) | 4.00 |
| Maximal Water content (LOD) | 10.00 |
| Nominal molar substitution | 0.90 |
| Minimum Molar substitution range | 0.81 |
| Maximum Molar substitution range | 0.99 |
| Solubility | Highly soluble in water. At high concentration, the wetting and dissolution time of the powder is delayed due to its low density and increased viscosity Soluble in ethanol. Freely soluble in propylen glycol. |