PEARLITOL® 100 SD - MANNITOL
PEARLITOL®
®Registered Trademark(s) of Roquette Frères
- Designed for direct compression
- For small particle size
Particle size mean diameter - 100 µm approx
Applications
- 1. Solid Forms - Tablets
- Chewable Tablets
- Swallowable Tablets
- Orally Dispersible Tablets
- Effervescent Tablets
- 2. Solid Forms - Capsules
- Hard Capsules Shell
- 5. Other Solid Forms
- Granules and Pellets
- 3. Films and coatings
- Film Coating
Functional properties
- Formulations Aids
- Fillers and Binders for Direct Compression
- Fillers and Binders for Roller Compaction
- Sensory Enhancers
- Stabilizers and Adjusters
- Stabilizers
Physical and chemical properties
- General Properties
- Label-friendly
- Plant-based & non-GMO
- Available with Food Grade for Nutraceuticals (some regions)
- Health & Nutritional Benefits
- Sugar-free
Documents
Product Specification Sheet
Name
Region
Size
Download
PEARLITOL® 100 SD
477,99 Ko
Region :
477,99 Ko
PEARLITOL® 100 SD
482,01 Ko
Region :
482,01 Ko
PEARLITOL® 100 SD
481,33 Ko
Region :
481,33 Ko
Safety Data Sheet
Name
Region
Language
Size
Download
PEARLITOL® 100 SD
Europe, BE
EN
519,61 Ko
Region : Europe, BE
EN
519,61 Ko
PEARLITOL® 100 SD - MANNITOL EP-USP
Americas, BR
EN
586,18 Ko
Region : Americas, BR
EN
586,18 Ko
PEARLITOL® 100 SD
Americas, CA
EN
288,00 Ko
Region : Americas, CA
EN
288,00 Ko
PEARLITOL® 100 SD
Europe, CH
EN
520,15 Ko
Region : Europe, CH
EN
520,15 Ko
PEARLITOL® 100 SD
Asia, CN
EN
339,11 Ko
Region : Asia, CN
EN
339,11 Ko
PEARLITOL® 100 SD
Europe, CY
EN
516,58 Ko
Region : Europe, CY
EN
516,58 Ko
PEARLITOL® 100 SD
Europe, DE
EN
522,94 Ko
Region : Europe, DE
EN
522,94 Ko
PEARLITOL® 100 SD
Europe, FI
EN
519,63 Ko
Region : Europe, FI
EN
519,63 Ko
PEARLITOL® 100 SD
Europe, BE
DE
532,42 Ko
Region : Europe, BE
DE
532,42 Ko
PEARLITOL® 100 SD
Europe, BE
FR
633,60 Ko
Region : Europe, BE
FR
633,60 Ko
PEARLITOL® 100 SD
Europe, BE
NL
528,33 Ko
Region : Europe, BE
NL
528,33 Ko
PEARLITOL® 100 SD
Europe, BG
BG
678,67 Ko
Region : Europe, BG
BG
678,67 Ko
PEARLITOL® 100 SD
Americas, BR
PT
538,65 Ko
Region : Americas, BR
PT
538,65 Ko
PEARLITOL® 100 SD
Americas, CA
FR
401,60 Ko
Region : Americas, CA
FR
401,60 Ko
PEARLITOL® 100 SD
Europe, CH
IT
621,86 Ko
Region : Europe, CH
IT
621,86 Ko
PEARLITOL® 100 SD
Europe, CH
DE
532,60 Ko
Region : Europe, CH
DE
532,60 Ko
PEARLITOL® 100 SD
Europe, CH
FR
634,11 Ko
Region : Europe, CH
FR
634,11 Ko
PEARLITOL® 100 SD
Asia, CN
ZH
560,15 Ko
Region : Asia, CN
ZH
560,15 Ko
PEARLITOL® 100 SD
Europe, CY
EL
670,96 Ko
Region : Europe, CY
EL
670,96 Ko
PEARLITOL® 100 SD
Europe, CY
TR
671,04 Ko
Region : Europe, CY
TR
671,04 Ko
PEARLITOL® 100 SD
Europe, CZ
CS
651,80 Ko
Region : Europe, CZ
CS
651,80 Ko
PEARLITOL® 100 SD
Europe, DE
DE
537,03 Ko
Region : Europe, DE
DE
537,03 Ko
PEARLITOL® 100 SD
Europe, DK
DA
528,47 Ko
Region : Europe, DK
DA
528,47 Ko
PEARLITOL® 100 SD
Europe, ES
ES
534,91 Ko
Region : Europe, ES
ES
534,91 Ko
PEARLITOL® 100 SD
Europe, FI
FI
535,59 Ko
Region : Europe, FI
FI
535,59 Ko
Get in touch with our Technical Experts
Please feel free to contact our technical experts for support during the development process.
Technical data
| Synonyms | D-Mannitol |
|---|---|
| CAS number | 69-65-8 |
| Physical form or apperance | White or almost white crystalline powder |
| Application | PEARLITOL® 100 SD mannitol is a direct compression excipient. It is a spray-dried form of mannitol with exceptional physical and chemical stability. It offers high API compatibility and no hygroscopicity. It is also a non-cariogenic and non-acidogenic sugar-free sweetener. It is suitable in formulations addressing all types of patient populations including pediatric and diabetic. It can be used in lozenges, swallowable tablets, orally dispersible tablets, chewable tablets, and effervescent tablets. |
| Teste/Odor | Slightly sweet and cooling effect. |
| Morphology |
|
| Water sorption isotherm at 20°C |
|
| Chemical Structure |
|
| Average molecular weight | 182.2 g/mol |
| Maximal Water content (LOD) | 0.50 |
| Solubility | Freely soluble in water (1 part in 5.5 part of water at 20°C), sparingly soluble in 95% ethanol (1 part in 83), practically insoluble in ether |
| Minimum melting temperature | 165 °C |
| Maximum melting temperature | 170 °C |
| Average mean particle diameter | 100 |
| dv10 Particle size distribution | 20 |
| dv50 Particle size distribution | 100 |
| dv90 Particle size distribution | 185 |
| Tablet Hardness |
|
| Experimental Conditions for Compression Behavior_Tablet Press | STYLCAM 200R |
| Experimental Conditions for Compression Behavior_Production Speed | 25 tablets/min (linear punch velocity: 96 mm/s; simulated rotary press speed: approximately 150000 tablets/hour) |
| Experimental Conditions for Compression Behavior_Tooling | Diameter 10 mm R9 concave |
| Experimental Conditions for Compression Behavior_Formuls | 98.8% PEARLITOL® 100 SD / 1.2% magnesium stearate |
| Experimental Conditions for Compression Behavior_Tablet Mass | 400 mg |
| Powder Flowability (according to Ph.Eur. 2.9.16, 10mm outflow opening) | 6 |
| Bulk Density (g/ml) | 0.47 |
| Tapped Density (g/ml) | 0.57 |
| True Density (g/ml) | 1.51 |
| Specific Surface Area (m²/g) | 1.05 |
| Angle of Repose (°) | 32 |