XYLISORB® XTAB 400
Xylitol granulated with Sodium Carboxymethyl Cellulose
Product Profile

XYLISORB® XTAB 400
Xylitol granulated with Sodium Carboxymethyl Cellulose

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Product Name

XYLISORB® XTAB 400 / Xylitol granulated with Sodium Carboxymethyl Cellulose

Synonyms

Xylitol-CMC sodium

Quantitative Composition

Approximately 98% of Xylitol / 2% of Sodium Carboxymethyl Cellulose

CAS Number

Xylitol 87-99-0; Sodium Carboxymethyl Cellulose 9004-32-4

Chemical Structure


Xylitol



Sodium Carboxymethyl Cellulose

Molecular Weight

Xylitol: 152.15 g/mol

Physical Form or Appearence

Off-white powder

Application

XYLISORB® XTAB 400 / Xylitol granulated with maize dextrin is a direct compression excipient and bulk sweetener. It is used in pharmaceutical and nutraceutical applications including swallowable tablets, effervescent tablets and medicated confectionary.

Water Content (LOD)

Nominal water content: 0.3%

Maximum water content: 0.5%

Morphology

Average Mean Particle Diameter

400 µm

Particle Size Distribution by Laser Diffraction

d10 (%vol)=158 µm

d50 (%vol)=314 µm

d90 (%vol)=567 µm

Solubility

Very soluble in water (solubility of xylitol in water is 1 part of xylitol for 1.6 part of water at 20°C)

Melting Temperature

92-94°C for xylitol

Water sorption isotherm at 20°C

Taste/Odor

Sweet (xylitol sweetening power is equivalent to sucrose) with cooling effect due to the high dissolution enthalpy of xylitol in water (153 J/g), odorless

Compression Behaviour

Experimental Conditions for Compression Behavior

Tablet Press STYLCAM 200R 
Production Speed 10, 25 and 40 tablets/min (Respective linear punch velocity: 38, 96 and 152 mm/s; Respective simulated rotary press speed: 60000, 150000 and 250000 tablets/hour) 
Tooling 16 mm Flat 
Lubrication 2.5% Magnesium stearate
Tablet Mass 1200 mg

Powder Characteristics

Powder Flowability:  10.8 s (according to Ph.Eur. 2.9.16, 10mm outlow opening)
Bulk Density: 0.54 g/cm3
Tapped Density: 0.68 g/cm3
True Density: 1.52 g/cm3
Specific Surface Area: below 0.2 m2/g
Angle of Repose: 40°