MICROCEL® MC-101
Microcrystalline Cellulose
| Product Name | MICROCEL® MC-101 |
| Generic Name | Microcrystalline Cellulose |
| Physico-chemical properties | |
| Compliance | EP/USP-NF/CHP |
| Synonyms | Cellulose, Microcrystalline |
| CAS Number | 9004-34-6 |
| Chemical Structure |
|
| Physical Form or Appearence | White, non-fibrous powder |
| Application | MICROCEL® MC-302 microcrystalline cellulose is a direct compression excipient for pharmaceutical oral dosage and nutraceutical forms (fiber source). It is also suitable for dry granulation. |
| Water content (LOD) |
Water Content (LOD) Maximum: 7 % |
| Morphology |
|
| Average mean particle diameter | 50 µm |
| Particle Size Distribution by Laser Diffraction |
dv10: 26 µm dv50: 81 µm dv90: 152 µm |
| Solubility | Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents |
| Water sorption isotherm at 20°C |
|
| Taste/Odor | Odorless and tasteless |
| Tablet hardness |
|
| Experimental Conditions for Compression Behavior |
Tablet Press: STYLCAM 200R Production Speed: 10, 25 and 40 tablets/min (respective linear punch velocity: 38, 96 and 152 mm/s; respective simulated rotary press speed: 60000, 150000 and 250000 tablets/hour) Tooling: Diameter 10 mm flat Formula: 100% MICROCEL® MC-101 Tablet Mass: 400 mg |
| Powder Characteristics |
Powder Flowability (according to Ph.Eur. 2.9.16, 25mm outflow opening): 8 s Bulk Density: 0.29 g/cm3 Tapped Density: 0.48 g/cm3 True Density: 1.54 g/cm3 Specific surface area: 1.27 m2/g |
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