KLEPTOSE® HPB Oral grade
Hydroxypropyl β-Cyclodextrin - Low molar substitution
Product Profile

KLEPTOSE® HPB Oral grade
Hydroxypropyl β-Cyclodextrin - Low molar substitution

EP/USP compliance

Product Name

KLEPTOSE® HPB Oral grade  Hydroxypropyl β-cyclodextrin

Synonyms

HYDROXYPROPYLBETADEX

CAS Number

128446-35-5

Chemical Structure

Molecular Weight

Nominal molecular weight: 1387 g/mol


Physical Form or Appearance

White or almost white amorphous powder.
The statistical hydroxypropylation of beta-cyclodextrin creates a multitude of molecules, differing by the position of the hydroxypropyl groups. Consequently, the product is not able to crystallize and remains in the amorphous state.

Application

KLEPTOSE® HPB Oral grade use is limited to oral dosage forms. It offers taste masking and solubility increase through molecular encapsulation.

Water content (LOD)

Nominal water content: 4 %

Maximum water content: 10 %

Degree of substitution

Nominal molar substitution: 0.62
Molar substitution range: 0.58-0.68

Solubility

Highly soluble in water. At high concentration, the wetting and dissolution time of the powder is delayed due to its low density and increased viscosity.
Soluble in ethanol.
Freely soluble in propylen glycol.

Water sorption isotherm at 20°C

Taste/Odor

Slightly sweet

Glass Transition Temperature vs. Water Content

Viscosity in Water

Surface Tension in Water

 

Disclaimer

® Registered trademark(s) of Roquette Frères. Any information provided herein is intended for healthcare and food industry professionals for internal use only and not to be delivered as such to final consumers. Information is based on our current state of knowledge and made available on an informational basis; products described may have restrictions with respect to their use, communication, and/or usage levels, and such may vary on a country-by-country basis. Manufacturers of dietary supplements should evaluate the intended use of the particular ingredient in their finished dietary supplement to confirm compliance with the applicable laws and regulations of authorities regulating such products, because the suitability and regulatory status of a product may be dependent on its specific intended use. As the use of these products is beyond our control, Roquette makes no express or implied warranties regarding the use of the product and no guarantee of product properties, and in particular no express or implied warranties regarding the use of the product in dietary supplements, including without limitation the implied warranties of merchantability and fitness for a particular purpose, and Roquette disclaims liability for any loss and/or damage related to such use. Roquette, further, does not warrant that the information or its use will not infringe any patent or other proprietary rights of any third party. Roquette providing this information is not a commitment to sell any product encompassing any of such information in the future.

Request a Document

Entering your details below will send your query to the relevant team for a swift and helpful response. We will not use your details for anything other than replying to your query.

Product Details

Your Details

* Required fields

Request A Document

{Market}

Submit > {Product} > {Usage Country}

Make An Inquiry

Entering your details below will send your query to the relevant team for a swift and helpful response. We will not use your details for anything other than replying to your query.

Product Details

Your Details

* Required fields

Make an Inquiry

{Market}

Submit > {Product} > {Usage Country}