Enable effective drug manufacturing and enhance patient compliance with our expansive range of reliable fillers and filler-binders.
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Roquette solutions for fillers, diluents, binders
Thanks to our wide range of fillers, diluents and binders, we can help you formulate a large variety of solid dosage forms: tablets, capsules, powders for sachets, etc.
Products particularly adapted to direct compression
Direct compression is a process that is becoming increasingly more important as it requires less drug stressing conditions than wet granulation and allows for improved productivity.
Roquette proposes a remarkable varied range of products suitable for the formulation of all types of tablets, ensuring good flowability, excellent compressibility and a specific particle size distribution to ensure uniform mixing. We offer multiple starches or starch compounds for swallowable / dispersible tablets.
PEARLITOL® FLASH mannitol-starch compound is an innovative coprocessed excipient for orodispersible tablets.
StarLac® lactose-starch compound is a co-processed excipient with unique tableting properties.
LYCATAB® C multifunctional starch excipient is a multifunctional starch excipient for capsules and tablets.
MICROCEL™ is a partially depolymerized cellulose, white, odorless and tasteless crystalline powder, composed by porous and high compressibility particles, ideal for tablets, capsules, granules and pellets.
Polyols with outstanding combination of chemical stability, great tasting and sugar-free properties.
PEARLITOL® SD mannitol and PEARLITOL® DC mannitol are part of a comprehensive range of granulated mannitol, adapted for swallowable / chewable / oral dispersible or effervescent tablets, used in challenging or unstable formulations.
We offer also a range of directly compressible polyols, such as SweetPearl® P DC maltitol for pleasant crunchy chewable tablets, NEOSORB® XTAB sorbitol for intense tasting suckable tablets or XYLISORB® XTAB xylitol for a cooling effect.
Cellulose with a wide variety of particle sizes and moisture content.
We offer a range of cellulose, MICROCEL™, to fit any process (direct compression, wet granulation, dry granulation, roller compaction), as well as moisture sensitive APIs.
Diluents
Diluents are inert powders acting as fillers in the formulation of tablets, capsules and powders for sachets. Roquette offers a range of both water-soluble and water-insoluble diluents that also have a disintegration function.
Starches or partially pregelatinized starches are traditional and trusted insoluble excipients, having the added function of disintegration aid: and extra white maize starch, Wheat starch TB, Potato starch supra NB bacterio, LYCATAB® C partially pregelatinized starch.
Highly functional polyols are appreciated for their physicochemical stability, organoleptic properties (sweetening power, cooling effect) and sugar-free, dietary benefits: NEOSORB® sorbitol powder, PEARLITOL® mannitol powder (crystalline, granulated), SweetPearl® maltitol powder.
The large range of soluble diluents includes also maltodextrins and dried glucose syrups, dextrose monohydrate and dextrose anhydrous.
Microcrystalline Cellulose (MCC) is widely used as a binder/diluent in oral tablet and capsule formulations, typically in dry granulation, wet granulation, and direct compression processes. In addition, MCC may also reduce friction during tablet ejection and facilitate tablet disintegration: MICROCEL™ 101, 102, 12, 112, 200.
Binders for wet granulation
Wet granulation, a traditional manufacturing process, is still widely used. It is often required when the pharmaceutical form contains a high level of active ingredients.
Roquette has specifically developed pharmaceutical binders with different degrees of water solubility or dispersibility.
LYCATAB® PGS is a cold water soluble starch, ideally used in high shear equipment.
LYCATAB® DSH is a water-soluble maltodextrin binder suitable for preparation of granulation solutions or use in dry blends.
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Designed with functionality and flexibility in mind, our range of binders enable robust formulations - no matter the process.See brochure -
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When it comes to meeting the challenges of formulation, you need more than just an ingredient supplier.See brochure -
![Tabulose]()
A co-processed product used as a secondary stabilizer and suspension agent in semi-solides formulas.See brochure -
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A partially depolymerized cellulose widely used in direct compression or in dry and wet granulation process.See brochure
More details on our selected solutions
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Roquette BioPharma solutions
Quality-based, safe, secure, and reliable supply of raw materials and excipients for biologics. -
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Pyrogen-free solutions for life-saving injectables
Pyrogen-free pure materials for parenteral preparations. -
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Direct compression: cost-effective solutions to optimise your formulations
Expertise from lab to pilot to industrial scale and a large range of high-quality excipients to reduce time-to-market. -
![pharma oral dosage tablets capsules]( "pharma oral dosage tablets capsules")
Disintegrants and superdisintegrants solutions
A range of sodium starch glycolates (GLYCOLYS® and EXPLOSOL®) and more than 30 years experience in the field to help in your formulations development. -
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Excipients for solubility and stability improvement & taste masking.
KLEPTOSE® betacyclodextrins range to improve the solubility or stability of active ingredients, or to improve the palatability of drugs. -
![pharma tablet film coating woman]( "pharma tablet film coating woman")
Coating solutions
A natural inert polymer (LYCOAT®) and a ready-to-use coating system (ReadiLYCOAT®) for fast aqueous film coating that saves up to 50% or more time. -
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Orodispersible solutions
Experience a uniquely pleasing taste and a simple tablet formulation thanks to PEARLITOL® Flash mannitol-starch compound.
Other solutions
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Coating
Use a film coating to mask unpleasant odors and tastes, and protect drugs from environmental factors. A benefit for both patient and laboratory. -
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Disintegrants and Superdisintegrants
Roquette's wide range of disintegration excipients facilitate the dissolution or release of the active ingredients of your capsules or tablets. -
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Solubility and stability improvement
Discover a full range range of solubilization and stability enhancers: native and hydroxypropyl cyclodextrins KLEPTOSE®, and octenyl succinate starches CLEARGUM® CO, for use in many dosage forms, from solid to liquid. -
![Taste-masking child syrup]( "Taste-masking child syrup")
Taste-masking
Discover our full range of KLEPTOSE®, efficient taste-masking agents adapted to all process and formulation constraints you might have. -
![pharma-oral-dosage-forms-syrup-little-boy]( "pharma-oral-dosage-forms-syrup-little-boy")
Liquid solutions
Roquette offers a large range of plant-based excipients for the formulation of liquid forms: syrups, solutions, ampoules, dispersions, etc.
Learn more about our solutions?
Your success is our greatest priority, and your needs are unique. We would love to better understand your needs and connect you with our experts.
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