
Diluents
Diluents are inert powders acting as fillers in the formulation of tablets, capsules and powders for sachets. Roquette offers a range of both water-soluble and water-insoluble diluents that also have a disintegration function.
Starches or partially pregelatinized starches are traditional and trusted insoluble excipients, having the added function of disintegration aid: and extra white maize starch, Wheat starch TB, Potato starch supra NB bacterio, LYCATAB® C partially pregelatinized starch.
Highly functional polyols are appreciated for their physicochemical stability, organoleptic properties (sweetening power, cooling effect) and sugar-free, dietary benefits: NEOSORB® sorbitol powder, PEARLITOL® mannitol powder (crystalline, granulated), SweetPearl® maltitol powder.
The large range of soluble diluents includes also maltodextrins and dried glucose syrups, dextrose monohydrate and dextrose anhydrous.
Microcrystalline Cellulose (MCC) is widely used as a binder/diluent in oral tablet and capsule formulations, typically in dry granulation, wet granulation, and direct compression processes. In addition, MCC may also reduce friction during tablet ejection and facilitate tablet disintegration: MICROCEL™ 101, 102, 12, 112, 200.
Binders for wet granulation
Wet granulation, a traditional manufacturing process, is still widely used. It is often required when the pharmaceutical form contains a high level of active ingredients.
Roquette has specifically developed pharmaceutical binders with different degrees of water solubility or dispersibility.
LYCATAB® PGS is a cold water soluble starch, ideally used in high shear equipment.
LYCATAB® DSH is a water-soluble maltodextrin binder suitable for preparation of granulation solutions or use in dry blends.
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Resources
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Enable effective drug manufacturing and enhance patient compliance with our expansive range of reliable fillers and filler-binders.See brochure
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Designed with functionality and flexibility in mind, our range of binders enable robust formulations - no matter the process.See brochure
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When it comes to meeting the challenges of formulation, you need more than just an ingredient supplier.See brochure
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A co-processed product used as a secondary stabilizer and suspension agent in semi-solid formulas.See brochure
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A partially depolymerized cellulose widely used in direct compression or in dry and wet granulation process.See brochure
More details on our selected solutions
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Roquette BioPharma solutions
Quality-based, safe, secure, and reliable supply of raw materials and excipients for biologics. -
Pyrogen-free solutions for life-saving injectables
Pyrogen-free pure materials for parenteral preparations. -
Direct compression: cost-effective solutions to optimise your formulations
Expertise from lab to pilot to industrial scale and a large range of high-quality excipients to reduce time-to-market. -
Disintegrants and superdisintegrants solutions
A range of sodium starch glycolates (GLYCOLYS® and EXPLOSOL®) and more than 30 years experience in the field to help in your formulations development. -
Excipients for solubility and stability improvement & taste masking.
KLEPTOSE® betacyclodextrins range to improve the solubility or stability of active ingredients, or to improve the palatability of drugs. -
Coating solutions
A natural inert polymer (LYCOAT®) and a ready-to-use coating system (ReadiLYCOAT®) for fast aqueous film coating that saves up to 50% or more time. -
Orodispersible solutions
Experience a uniquely pleasing taste and a simple tablet formulation thanks to PEARLITOL® Flash mannitol-starch compound.
Other solutions
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Coating
Use a film coating to mask unpleasant odors and tastes, and protect drugs from environmental factors. A benefit for both patient and laboratory. -
Disintegrants and Superdisintegrants
Roquette's wide range of disintegration excipients facilitate the dissolution or release of the active ingredients of your capsules or tablets. -
Solubility and stability improvement
Discover a full range range of solubilization and stability enhancers: native and hydroxypropyl cyclodextrins KLEPTOSE®, and octenyl succinate starches CLEARGUM® CO, for use in many dosage forms, from solid to liquid. -
Taste-masking
Discover our full range of KLEPTOSE®, efficient taste-masking agents adapted to all process and formulation constraints you might have. -
Liquid solutions
Roquette offers a large range of plant-based excipients for the formulation of liquid forms: syrups, solutions, ampoules, dispersions, etc.
