Roquette Disintegrants and Superdisintegrants

Disintegrants and superdisintegrants are used in tablets and capsules to ensure the rapid break down into their primary particles, facilitating the dissolution or release of the active ingredients. Roquette has developed a versatile range of standard disintegration excipients.

Super-désintégrant GLYCOLYS®

La gamme s'élargit encore au super-désintégrant GLYCOLYS® glycolates d'amidon sodique, avec trois grades uniques pour répondre à vos besoins spécifiques de formulation :

  • GLYCOLYS® LV, pour les procédés de granulation humide et de granulation à fort taux de cisaillement.
  • GLYCOLYS® Low pH, adapté aux médicaments sensibles au pH.
  • GLYCOLYS®, pour toutes les autres exigences.

Le principal avantage de GLYCOLYS® est sa polyvalence :

  • Adapté aux formes posologiques orales (comprimés et gélules) et à tous les procédés de fabrication : compression directe ou granulation humide, y compris procédés de granulation à fort taux de cisaillement.
  • Efficacité non altérée par les lubrifiants.
  • Différents modes d'incorporation sont possibles (intra ou extragranulaire ; voire les deux si possible).

Roquette range of disintegrants and self disintegrating compounds

A range of traditional native starches

  • Our partially pregelatinised starch LYCATAB® C, which contains native starch which ensures a rapid disintegration and drug release.
  • The innovative multifunctional starch compound StarLac®, which consists of lactose and maize starch particles in granular form. With optimized self-disintegration properties, it is therefore well adapted to all types of formulations, especially for tablets requiring fast disintegration.

A mannitol-starch compound

  • PEARLITOL® FLASH mannitol-starch compound is an innovative mannitol-starch compound for orodispersible tablets.

Find out more about our solutions for disintegrants

More details on our selected solutions

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    Liquid solutions

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