Roquette Disintegrants and Superdisintegrants

Disintegrants and superdisintegrants are used in tablets and capsules to ensure the rapid break down into their primary particles, facilitating the dissolution or release of the active ingredients. Roquette has developed a versatile range of standard disintegration excipients.

Roquette superdisintegrant GLYCOLYS®

The range further extends to superdisintegrant GLYCOLYS®, a range of sodium starch glycolates with three unique grades to meet specific formulation needs:

  • GLYCOLYS® LV, for wet granulation and high-shear granulation processes.
  • GLYCOLYS® Low pH, suitable for pH sensitive drugs.
  • GLYCOLYS®, for all other requirements.

The main advantage of GLYCOLYS® is its versatility:

  • Suitable for all oral dosage forms (tablets and capsules) and for all manufacturing processes: direct compression or wet granulation, including high-shear granulation processes.
  • Efficiency unaffected by lubricants.
  • Different modes of incorporation are possible (intra /or extra granularly; even mixed is possible).

Roquette range of disintegrants and self disintegrating compounds

A range of traditional native starches

  • Our partially pregelatinised starch LYCATAB® C, which contains native starch which ensures a rapid disintegration and drug release.
  • The innovative multifunctional starch compound StarLac®, which consists of lactose and maize starch particles in granular form. With optimized self-disintegration properties, it is therefore well adapted to all types of formulations, especially for tablets requiring fast disintegration.

A mannitol-starch compound

  • PEARLITOL® FLASH mannitol-starch compound is an innovative mannitol-starch compound for orodispersible tablets.

Find out more about our solutions for disintegrants

More details on our selected solutions

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