Roquette has developed LYCATAB® C as a filler-disintegrant for two-piece hard gelatine capsules. The study compares the performance of LYCATAB® C with the similar excipient Starch 1500® in this application. Partially pregelatinized corn starches are free-flowing and self-disintegrating powders. Their physico-chemical properties are well adapted to the use as filler-disintegrant in two-piece hard gelatin capsules. LYCATAB® C has been developed for this application.

The following study has been done to compare the performance of LYCATAB® C with the similar excipient Starch 1500® in its recommended application as filler for two-piece hard gelatin capsules. The more compact structure of LYCATAB® C seems to be important for getting optimal results in capsules production.

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