To get the required rheological properties several hydrosoluble polymers and plasticizers are generally selected. Using only one polymer, a non-GMO pregelatinized hydroxypropyl pea starch, LYCOAT® RS720, we obtained the desired mechanical, rheological, and functional properties. Using the film casting technique (at room temperature) we obtained an ODF construct having good drug uniformity and dissolution performance.
Case study: KLEPTOSE® BIOPHARMA as a potential functional alternative to surfactants within biologic formulationsKLEPTOSE® BioPharma (hydroxypropyl beta cyclodextrin) represents a promising alternative to surfactants commonly used within biologic formulations, such as polysorbates.
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