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Ampelopsin (AMP) or better known under the name of Dihydromyricetin is a flavonoid extract with many pharmacological properties such as anti-inflammatory, antimicrobial, antioxidant, hepatoprotective and anti-carcinogenic. Its development into a formulation for oral administration is limited due to its low water solubility and bioavailability beside light sensitivity.
The objective of this study was to evaluate the ability of native and modified β-cyclodextrins to enhance AMP solubility and stability.