Please note our Product Finder does not contain our complete product portfolio. Should you wish for further information on a specific product, please contact us.
Contact customer care
Roquette at PBI BioProcess International 2022


San Diego, USA

Welcome to our booth #408

The Roquette Team will present you our solutions for biotherapeutics, which come with:

  • High-quality ingredients for upstream, downstream, and final formulation.
  • Expertise to help enhance processes and quality.
  • Formulation support.

You can start exploring our solutions now: visit our Innovation Hub or browse our product finder.

Welcome to a Scientific presentation on Cell Culture

Ketaki Patwardhan PhD, Technical Developer at Roquette, will present the works carried out by Hailong Zhang, PhD, Analytical Research Manager, Applied Science at Roquette Asia Pacific (Singapore):

  • Topic: Polysorbates versus hydroxypropyl-betacyclodextrin (HPBCD) stability comparative study and their monoclonal antibody stability benefits
    Polysorbates are intensively used in biologics formulation as stabilizer due to their propensity to inhibit aggregation at interfaces but possesses low intrinsic stability. This study is focusing on bringing to formulator attention, as an alternative, a new class of molecules hydroxypropyl-betacyclodextrin (HPBCD). When subjected to various physical and chemical stressors: heat, light and oxidative stresses, HPBCD maintains its chemical stability with >97% recovery while polysorbate showed significant degradation. For adalimumab, as a model mAb, formulated in presence of HPBCD we observed a significant decrease in both agitation and thermal stress-induced protein aggregation and sub-visible particle formation prevention compared to polysorbate.
  • Where: Track 2: Cell Culture - Room 10
  • When: Tuesday, 15 March 2022 11:30am - 12:00pm - PST/PDT (Pacific Daylight, GMT-7)


Looking forward to meeting you!

Learn more and register


Hailong ZHANGHailong Zhang, PhD, Analytical Research Manager, Applied Science, Roquette Asia Pacific (Singapore)

Dr. Hailong Zhang is analytical research manager in applied science at Roquette. Dr. Zhang received his Ph.D. in Analytical-bioanalytical Chemistry at Cleveland State university /Cleveland Clinic and completed postdoctoral training in pharmaceutical science at University of Toronto. Dr. Zhang’s interests and experience focus on exploring phase-appropriate analytical strategies to the specific needs of unique molecules, delivering a comprehensive understanding and characterization of the molecule for each stage of drug development and commercialization, including starting material, intermediates and drug products under cGMP.

Ketaki PARTWARDHAN Ketaki Patwardhan Ph.D, Pharma Technical Developer, Roquette