Hydroxypropyl Beta-cyclodextrin HPB-LB Parenteral grade
KLEPTOSE® HPB-LB is a hydroxypropyl beta-cyclodextrin parenteral grade material that is used as an encapsulating agent for Rx injectables. It is a modified betacyclodextrin for parenteral use. Modified beta-cyclodextrins used in parenteral preparations provide active substance stabilization improvement against light and oxidation as well as enhancement of solubilization of active pharmaceutical ingredients.
Molecular encapsulation with modified betacyclodextrins has become an accepted and useful tool for pharmaceutical developers. There are currently several pharmaceutical products containing modified cyclodextrin complexes on the market. Roquette has pioneered the industrial development of cyclodextrins with its KLEPTOSE® range of betacyclodextrins.
Hydroxypropyl betacyclodextrin (HPBCD) is a white, amorphous powder. The HPBCD molecule is a torus shaped ring with a polar hydrophilic outside and an apolar hydrophobic cavity.