PEARLITOL® Flash
Co-processed Mannitol Starch
Product Profile

PEARLITOL® Flash
Co-processed Mannitol Starch

EP/USP/JP compliance

 

Product Name

PEARLITOL® Flash Co-processed Mannitol Starch

Synonyms

D-Mannitol

Quantitative Composition

Approximately D-Mannitol 80%-Extra White Maize Starch 20%

CAS Number

D-Mannitol 69-65-8; Maize Starch 9005-25-8

Chemical Structure

D-MannitolStarch

 

 

 

Molecular Weight

Mannitol: 182.17 g/mol

Physical Form or Appearence

White powder

Application

PEARLITOL® Flash is a direct compression excipient with disintegrant properties. It offers excellent chemical inertness and consistent rapid disintegration time. It brings a pleasant taste and texture and is suitable for swallowable and orally dispersible tablets.

Water Content (LOD)

Maximum water content: 3 %

Morphology

Average Mean Particle Diameter

200 µm

Particle Size Distribution by Laser Diffraction

dv10 = 80 µm

dv50 = 200 µm

dv90 = 300 µm

Solubility

Partially soluble in cold water, practically insoluble in ethanol (96%)

Melting Temperature

166-170°C for D-Mannitol

Water sorption isotherm at 20°C

Taste/Odor

Slightly sweet (sweetening power of mannitol about 70% that of sucrose)

Compression Behaviour

Experimental Conditions for Compression Behavior

Tablet Press  STYLCAM 200R 
Production Speed  10 tabs/min (Linear punch velocity: 38 mm/s ; Simulated rotary press speed: 60000 tablets/hour) 
Tooling  10 mm Flat 
Lubrication  1.2% Magnesium stearate 

Powder Characteristics

Powder Flowability: 5 s (according to Ph.Eur. 2.9.16, 10mm outflow opening)
Bulk Density: 0.52 g/cm3
Tapped Density: 0.65 g/cm3
True Density: 1.503 g/cm3
Specific Surface Area: 0.55 m²/g
Angle of Repose: 40°