NEOSORB® P 650 C
Product Profile

NEOSORB® P 650 C

Sorbitol

EP/USP compliance

 

Product Name

NEOSORB® P 650 C sorbitol

Synonyms

D-Glucitol

CAS Number

50-70-4 

Chemical Structure

Molecular Weight

182.2 g/mol

Physical Form or Appearence

White or almost white crystalline powder

Application

NEOSORB® P 650 C sorbitol is a filler and filler-binder excipient with excellent tableting properties. It is a non-cariogenic and non-acidogenic sugar-free sweetener that is suitable for chewable, suckable or effervescent tablets

Water Content (LOD)

Nominal water content: 0.2 %

Maximum water content: 1.5 %

Morphology

Average Mean Particle Diameter

650 µm

Solubility

Very soluble in water (235 g/100 ml at 25°C), practically insoluble in ethanol (96%)

Melting Temperature

95-98°C

Water sorption isotherm at 20°C

Taste/Odor

Slightly sweet (sweetening power about 50-60% that of sucrose) with cooling effect due to high dissolution enthalpy in water (111 J/g)

Compression Behaviour

Experimental Conditions for Compression Behavior

Tablet Press  STYLCAM 200R 
Production Speed  10 tablets/min (linear punch velocity: 38 mm/s; simulated rotary press speed: approximately 60000 tablets/min) 
Tooling  Diameter 10 mm R9 Concave
Lubrication  0.7% magnesium stearate 
Tablet Mass  400 mg 

Powder Characteristics

Powder Flowability: 11 s
Bulk Density: 0.67 g/cm3
Tapped Density: 0.69 g/cm3
True Density: 1.507 g/cm3
Specific Surface Area: 2 m²/g
Angle of Repose: 38°