MICROCEL™ 302 SD
Microcrystalline Cellulose
Product Profile

MICROCEL™ 302 SD
Microcrystalline Cellulose

EP/USP-NF/JP compliance

 

Product Name

MICROCEL™ 302 SD Microcrystalline Cellulose

Synonyms

Cellulose, Microcrystalline

CAS Number

9004-34-6

Chemical Structure

Physical Form or Appearence

White, non-fibrous powder

Application

MICROCEL™ 302 SD Microcrystalline Cellulose is a direct compression excipient for pharmaceutical oral dosage and nutraceutical forms (fiber source). It is also suitable for dry granulation. MICROCELTM 302 SD is a spray-dried product from EXCiPACT (International Pharmaceutical Excipients Certification) certified plant.  

Water Content (LOD)

Maximum water content: 5%

Morphology

Average Mean Particle Diameter

100 µm

Particle Size Distribution by Laser Diffraction

dv10 = 14 µm

dv50 = 72 µm

dv90 = 190 µm

Solubility

Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents.

Water sorption isotherm at 20°C

Taste/Odor

Odorless and tasteless  

Compression Behaviour

Experimental Conditions for Compression Behavior

Tablet Press  STYLCAM 200R 
Production Speed  10 and 40 tablets/min (Respective linear punch velocity: 38 and 152 mm/s; Respective Simulated rotary press speed: 60000 and 250000 tablets/hour) 
Tooling  10 mm Flat punch 
Lubrication  No lubricant 
Tablet Mass  400 mg 

Powder Characteristics

Bulk Density: 0.42 g/cm3 (according to Ph.Eur. 2.9.16, 25mm outflow opening)
Tapped Density: 0.61 g/cm3
True Density: 1.54 g/cm3
Specific Surface Area: 1.17 m²/g
Angle of Repose: 43°