MICROCEL® MC-302
Microcrystalline Cellulose
Product Profile

MICROCEL® MC-302
Microcrystalline Cellulose

 

Product Name MICROCEL® MC-302
Generic Name Microcrystalline Cellulose
Physico-chemical properties
Compliance EP/USP-NF
Synonyms Cellulose, Microcrystalline
CAS Number 9004-34-6
Chemical Structure
Physical Form or Appearence White, non-fibrous powder
Application MICROCEL® MC-302 microcrystalline cellulose is a direct compression excipient for pharmaceutical oral dosage and nutraceutical forms (fiber source). It is also suitable for dry granulation.
Water content (LOD)

Water Content (LOD) Maximum: 7 %

Morphology
Average mean particle diameter 100 µm
Particle Size Distribution by Laser Diffraction

dv10: 33 µm

dv50: 98 µm

dv90: 240 µm

Solubility Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents
Water sorption isotherm at 20°C
Taste/Odor Odorless and tasteless
Tablet hardness
Experimental Conditions for Compression Behavior

Tablet Press: STYLCAM 200R

Production Speed: 10, 25 and 40 tablets/min (respective linear punch velocity: 38, 96 and 152 mm/s ; respective simulated rotary press speed: 60000, 150000 and 250000 tablets/hour)

Tooling: Diameter 10 mm flat

Formula: 99.9% MICROCEL® MC-302 / 0.1% Fumed silica

Tablet Mass: 400 mg

Powder Characteristics

Powder Flowability (according to Ph.Eur. 2.9.16, 10mm outflow opening): Not free-flowing

Bulk Density: 0.4 g/cm3

Tapped Density: 0.54 g/cm3

True Density: 1.54 g/cm3

Specific surface area: 1 m2/g

Angle of Repose: 38 °

 

Disclaimer

These typical values are provided for information only and we believe them to be reliable. Methods available upon request.

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